Results 31 to 40 of about 1,115,146 (219)

Vertical transmission of maternal COVID-19 antibodies after CoronaVac vaccine: A case report

Revista da Sociedade Brasileira de Medicina Tropical, 2021
The use of coronavirus disease 2019 RNA vaccines in pregnant women led to reports on the first cases of newborns with antibodies to sudden acute respiratory syndrome coronavirus 2 (SARS-CoV-2), a phenomenon that was unknown when using immunizations with ...
Bruno Thizon Menegali, Fabiana Schuelter-Trevisol, Alexandre Naime Barbosa, Talita Menegali Izidoro, Otto Henrique May Feurschuette, Chaiana Esmeraldino Mendes Marcon, Daisson José Trevisol   +6 more
doaj   +1 more source

Simplified monomeric VHH-Fc antibodies provide new opportunities for passive immunization.

Current Opinion in Biotechnology, 2019
Simplified monomeric monoclonal antibodies consisting of a single-domain VHH, derived from camelid heavy-chain only antibodies, fused with the Fc domain of either IgG (VHH-IgG) or IgA (VHH-IgA) antibodies, are promising therapeutic proteins.
H. De Greve, V. Virdi, Shruti Bakshi, A. Depicker   +3 more
semanticscholar   +1 more source

A brief history of antibody-based therapy

Neurobiology of Disease, 2019
Active and passive immunization have been used to treat human disease for hundreds of years and improvements in technology and knowledge is only increasing the number of therapeutic applications.
M. Alpaugh, F. Cicchetti
doaj   +1 more source

Active and passive immunizations with HtsA, a streptococcal heme transporter protein, protect mice from subcutaneous group A Streptococcus infection

Journal of Microbiology, Immunology and Infection, 2020
Background/Purpose: HtsA (Streptococcus heme transporter A) is the lipoprotein component of the streptococcal heme ABC transporter (HtsABC). The aim of this study is to investigate whether the HtsA protein has immunoprotective effect against group A ...
Yingli Song, XiaoLan Zhang, Minghui Cai, Chunmei Lv, Yuan Zhao, Deqin Wei, Hui Zhu   +6 more
doaj   +1 more source

T cell mediated cerebral hemorrhages and microhemorrhages during passive Aβ immunization in APPPS1 transgenic mice

Molecular Neurodegeneration, 2011
Background Immunization against amyloid-β (Aβ), the peptide that accumulates in the form of senile plaques and in the cerebrovasculature in Alzheimer's disease (AD), causes a dramatic immune response that prevents plaque formation and clears accumulated ...
de Calignon Alix, Spires-Jones Tara L, Mielke Matthew, Mora J Rodrigo, Meyer-Luehmann Melanie, von Andrian Ulrich H, Hyman Bradley T   +6 more
doaj   +1 more source

The burden of COVID-19 in a heterogeneous population of immunocompromised patients – realities of the postpandemic

Терапевтический архив, 2023
On July 3, 2023, an interdisciplinary Council of Experts The burden of COVID-19 in a heterogeneous population of immunocompromised patients post-pandemic realities was held in Moscow with leading experts in pulmonology, rheumatology, hematology ...
Sergey N. Avdeev, Vladimir P. Chulanov, Ekaterina I. Alexeeva, Olga A. Aleshina, Aleksey V. Bereznikov, Oleg N. Kotenko, Aleksander M. Lila, Zinaida Yu. Mutovina, Elena N. Parovichnikova, Daria S. Fomina, Nadiya F. Frolova, Alexey O. Shevchenko   +11 more
doaj   +1 more source

Early-Onset Network Hyperexcitability in Presymptomatic Alzheimer’s Disease Transgenic Mice Is Suppressed by Passive Immunization with Anti-Human APP/Aβ Antibody and by mGluR5 Blockade

Frontiers in Aging Neuroscience, 2017
Cortical and hippocampal network hyperexcitability appears to be an early event in Alzheimer’s disease (AD) pathogenesis, and may contribute to memory impairment.
S. Kazim, S. Chuang, Wangfa Zhao, R. Wong, R. Bianchi, K. Iqbal   +5 more
semanticscholar   +1 more source

Emerging antibody-based products for infectious diseases: Planning for metric ton manufacturing

Human Vaccines & Immunotherapeutics, 2022
This review focuses on the emerging monoclonal antibody market for infectious diseases and the metric ton scale manufacturing requirements to meet global demand.
Kevin J Whaley, Larry Zeitlin
doaj   +1 more source

Immunization With Recombinant Haemonchus contortus Y75B8A.8 Partially Protects Local Crossbred Female Goats From Haemonchus contortus Infection

Frontiers in Veterinary Science, 2022
Haemonchus contortus Y75B8A.8 (Hc8) derived from H. contortus excretory–secretory (ES) products was identified as a functional inhibitor of goat interleukin 2 (IL-2). It may act as a vaccine candidate for the development of therapeutic strategies against
Xiaowei Tian, Xiaowei Tian, Mingmin Lu, Yongqian Bu, Yang Zhang, Kalibixiati Aimulajiang, Meng Liang, Charles Li, Ruofeng Yan, Lixin Xu, Xiaokai Song, Xiangrui Li, Xiangrui Li   +12 more
doaj   +1 more source

Tau passive immunization blocks seeding and spread of Alzheimer hyperphosphorylated Tau-induced pathology in 3 × Tg-AD mice

Alzheimer's Research & Therapy, 2018
Accumulating evidence indicates that Tau pathology can spread from neuron to neuron by intake and coaggregation of the hyperphosphorylated Tau (p-Tau) seeds with the host neuron protein.
Chun-ling Dai, Wen Hu, Y. Tung, Fei Liu, C. Gong, K. Iqbal   +5 more
semanticscholar   +1 more source