Results 71 to 80 of about 1,115,146 (219)

Immunotherapy for Alzheimer’s Disease: Past, Present and Future

Frontiers in Aging Neuroscience, 2014
Alzheimer’s disease (AD) is an incurable, progressive, neurodegenerative disorder affecting over 5 million people in the US alone. This neurological disorder is characterized by widespread neurodegeneration throughout the association cortex and limbic ...
Brian eSpencer, Eliezer eMasliah
doaj   +1 more source

Generation of a recombinant chickenized monoclonal antibody against the neuraminidase of H9N2 avian influenza virus

AMB Express, 2020
We previously reported a monoclonal antibody (mAb), 1G8, against the neuraminidase (NA) of H9N2 avian influenza virus (AIV) with significant NA inhibitory activity.
Fei Wang, Yajuan Wang, Zhimin Wan, Hongxia Shao, Kun Qian, Jianqiang Ye, Aijian Qin   +6 more
doaj   +1 more source

Nanobody–chlorin e6 conjugate for Nectin‐4‐mediated tumor targeting and enhanced photodynamic therapy

VIEW, EarlyView.
Nectin‐4 is frequently overexpressed in solid tumors, yet many PDT photosensitizers show poor water solubility and nonspecific uptake. A Nectin‐4‐targeted nanobody–chlorin e6 conjugate (NPC) improves aqueous solubility and selectively accumulates in Nectin‐4‐positive tumor cells.
Haodian Wan, Tao Ye, Yawei Bi, Jiayu Zhang, Wei Wu, Aochi Liu, Li Sun, Jie Lin, Ningli Chai, Manjie Zhang, Jian Ma   +10 more
wiley   +1 more source

Passive immunization by recombinant ferric enterobactin protein (FepA) from Escherichia coli O157

Iranian Journal of Microbiology, 2013
Background and Objectives: Enterohemorrhagic Escherichia coli (EHEC) O157:H7 has been recognized as a major food borne pathogen responsible for frequent hemorrhagic colitis and hemolytic uremic syndrome in humans.
Seyed-Mehdi Larrie-Bagha, Iraj Rasooli, Seyed-Latif Mousavi-Gargari, Zohreh Rasooli, Shahram Nazarian   +4 more
doaj  

Current and Novel Approaches in Influenza Management

Vaccines, 2019
Influenza is a disease that poses a significant health burden worldwide. Vaccination is the best way to prevent influenza virus infections. However, conventional vaccines are only effective for a short period of time due to the propensity of influenza ...
Erasmus Kotey, Deimante Lukosaityte, Osbourne Quaye, William Ampofo, Gordon Awandare, Munir Iqbal   +5 more
doaj   +1 more source

Passive Immunization with Phospho-Tau Antibodies Reduces Tau Pathology and Functional Deficits in Two Distinct Mouse Tauopathy Models

PLoS ONE, 2015
In Alzheimer’s disease (AD), an extensive accumulation of extracellular amyloid plaques and intraneuronal tau tangles, along with neuronal loss, is evident in distinct brain regions. Staging of tau pathology by postmortem analysis of AD subjects suggests
S. Sankaranarayanan, D. Barten, L. Vana, N. Devidze, Ling Yang, G. Cadelina, N. Hoque, L. Decarr, S. Keenan, Alan X. Lin, Yang Cao, B. Snyder, Bin Zhang, Magdalena Nitla, Gregg Hirschfeld, N. Barrezueta, C. Polson, P. Wes, V. Rangan, A. Cacace, C. Albright, J. Meredith, J. Trojanowski, V. Lee, K. Brunden, M. Ahlijanian   +25 more
semanticscholar   +1 more source

Major Cat Allergen Fel d 4: Structure and Identification of a Cross‐Reactive IgE‐Epitope‐Containing Area

Allergy, EarlyView.
This study reports the three‐dimensional structure of an important cat allergen, Fel d 4, that shares high homology with Equ c 1 (i.e., major horse allergen) and Can f 6 (i.e., dog allergen). The C‐terminal region of the Fel d 4 contains a major IgE‐reactive epitope.
Nikolina Todorović, Daria Trifonova, Zicheng Liu, Mirela Curin, Laszlo Schooltink, Theo Sagmeister, Christoph Grininger, Renata Kiss, Nina Gottstein, Bernd Gesslbauer, Andreas Winkler, Tea Pavkov‐Keller, Alexander Karaulov, Rudolf Valenta, Walter Keller   +14 more
wiley   +1 more source

Passive Immunization

Citation: 'passive immunization' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13540 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms ...
  +5 more sources

Repertoire characterization and validation of gB-specific human IgGs directly cloned from humanized mice vaccinated with dendritic cells and protected against HCMV.

PLoS Pathogens, 2020
Human cytomegalovirus (HCMV) causes serious complications to immune compromised hosts. Dendritic cells (iDCgB) expressing granulocyte-macrophage colony-stimulating factor, interferon-alpha and HCMV-gB were developed to promote de novo antiviral adaptive ...
Sebastian J Theobald, Christoph Kreer, Sahamoddin Khailaie, Agnes Bonifacius, Britta Eiz-Vesper, Constanca Figueiredo, Michael Mach, Marija Backovic, Matthias Ballmaier, Johannes Koenig, Henning Olbrich, Andreas Schneider, Valery Volk, Simon Danisch, Lutz Gieselmann, Meryem Seda Ercanoglu, Martin Messerle, Constantin von Kaisenberg, Torsten Witte, Frank Klawonn, Michael Meyer-Hermann, Florian Klein, Renata Stripecke   +22 more
doaj   +1 more source

Allergic Sensitization to Inhalant Allergens in the Upper Respiratory Tract—the B Cell Side

Allergy, EarlyView.
ABSTRACT Allergic diseases are on the rise worldwide, driven by respiratory epithelial barrier dysfunction that promotes sensitization to inhalant allergens such as pollen, dust mites, pet dander, and fungal spores. These antigens trigger IgE‐mediated immune responses that lead to diseases such as allergic rhinitis (AR) and asthma.
Ola Grimsholm, Mohammed Zghaebi, Bita Hambrecht, Tanja Kalic, Christopher C. Udoye, Rudolf Manz, Barbara Bohle, Katarzyna M. Sitnik, Julia Eckl‐Dorna, Heimo Breiteneder   +9 more
wiley   +1 more source