Results 51 to 60 of about 15,289,136 (259)

The Hereford Screen: A Prehistory

, 2017
This paper explores two contexts for Francis Skidmore and George Gilbert Scott's screen at Hereford Cathedral. First, it locates the screen within a succession of choir screens at Hereford from the middle ages to the present, thereby charting the ...
The Hereford Screen: A Prehistory
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Passively sensing smartphone use in teens with rates of use by sex and across operating systems

Scientific Reports
Youth screen media activity is a growing concern, though few studies include objective usage data. Through the longitudinal, U.S.-based Adolescent Brain Cognitive Development (ABCD) Study, youth (mage = 14; n = 1415) self-reported their typical ...
Jordan D. Alexander, Janosch Linkersdörfer, Katherine Toda-Thorne, Ryan M. Sullivan, Kevin M. Cummins, Rachel L. Tomko, Nicholas B. Allen, Kara S. Bagot, Fiona C. Baker, Bernard F. Fuemmeler, Elizabeth A. Hoffman, Orsolya Kiss, Michael J. Mason, Tam T. Nguyen-Louie, Susan F. Tapert, Calen J. Smith, Lindsay M. Squeglia, Natasha E. Wade   +17 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source

Cajoling screen media students back on-campus – and keeping them there!

, 2023
Research shows that in today’s post-COVID era, “student engagement” at university has declined, and with it, attrition has increased. Like many universities, a cohort of students at the researchers’ university are dissatisfied with rapid online learning ...
Bentley, Rachel (R15033), Dawkins, Roger (R17765)   +1 more
core  

Can mindfulness play a role in building social-emotional capacities among youth exposed to screens?

Frontiers in Psychiatry, 2023
IntroductionIncreased screen time coupled with public safety restrictions may pose a serious challenge to adequate social-emotional development in youth during the pandemic.
Soyeon Kim, Soyeon Kim, Stephanie Munten, Shavon Stafford, Nathan J. Kolla, Nathan J. Kolla   +5 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A passive heat maintenance strategy implemented during a simulated half-time improves lower body power output and repeated sprint ability in professional Rugby Union players [PDF]

, 2015
Reduced physical performance has been observed following the half-time period in team sports players, likely due to a decrease in muscle temperature during this period.
Liam Kilduff, Marc A Briggs, Richard Bracken, Thibault Giroud, Gill, Nicholas, Cook Christian J., Gill Nicholas, Thibault Giroud (705120), Nicholas Gill (705121), Briggs Marc A., Kilduff, L.P., Bracken Richard M., Russell Mark, Kilduff Liam P., Christian J Cook, Giroud, T., Giroud Thibault, Russell, Mark, Daniel J West, West Daniel J., Briggs, Marc, Kilduff, Liam, Bracken, R.M., Liam P Kilduff, Gill, N., Bracken, Richard, Daniel J. West (568058), Liam P. Kilduff (705122), Russell, M., Nicholas Gill, Richard M. Bracken (568056), Briggs, M.A., Cook, C.J., Mark Russell (206029), Mark Russell, Kilduff, Liam P, West, D.J., Cook, Christian, Christian J. Cook (654963), West, Dan, Giroud, Tibault, Richard M Bracken, Marc A. Briggs (705119)   +42 more
core   +2 more sources

Screen time in preschool-aged children [PDF]

Multidisciplinarni Pristupi u Edukaciji i Rehabilitaciji
The World Health Organization defines sedentary screen time as the time spent in passive screenbased entertainment (TV, computer, mobile phone), excluding active screen time, specifically time spent playing games requiring physical activity or movement ...
Ana Madžar Čančar, Slađana Ćalasan, Bojana Vuković, Sanja Živanović, Bojana Mastilo, Andrijana Bakoč, Ivana Zečević   +6 more
doaj   +1 more source

mPulse Mobile Sensing Model for Passive Detection of Impulsive Behavior: Exploratory Prediction Study

JMIR Mental Health, 2021
BackgroundMobile health technology has demonstrated the ability of smartphone apps and sensors to collect data pertaining to patient activity, behavior, and cognition.
Wen, Hongyi, Sobolev, Michael, Vitale, Rachel, Kizer, James, Pollak, J P, Muench, Frederick, Estrin, Deborah   +6 more
doaj   +1 more source