Results 41 to 50 of about 403,948 (291)

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

open access: yesFEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand   +2 more
wiley   +1 more source

Agricultural land use in Danish organic pig production [PDF]

open access: yes, 2018
In Denmark the organic sows farrow outdoor on pasture (picture 1) and the gestation sows are outdoor from 15 April to 1 November on pasture (picture 2). Some farmers also keep their weaned piglets on outdoor pasture (picture 3). In the project pEcosystem
Knage-Drangsfeldt, Kristian
core  

Relationships between land use and nitrogen and phosphorus in New Zealand lakes [PDF]

open access: yes, 2011
Developing policies to address lake eutrophication requires an understanding of the relative contribution of different nutrient sources and of how lake and catchment characteristics interact to mediate the source–receptor pathway.
Abell, Jonathan Michael   +3 more
core   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

open access: yesFEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida   +6 more
wiley   +1 more source

From technology transfer to innovation-based rural development: A necessary turn at the Indio Hatuey experimental station

open access: yesElementa: Science of the Anthropocene, 2018
The collapse of the socialist bloc in the early 1990s led to a severe economic crisis in Cuba, unleashing various processes of change to confront the situation.
Taymer Miranda Tortoló   +7 more
doaj   +1 more source

Comparison of Spider Populations of Ground Stratum in Arkansas Pasture and Adjacent Cultivated Field [PDF]

open access: yes, 1963
Of 64 species of spiders taken from the ground stratum of an Arkansas pasture and adjoining cotton field, only 26 were common to both. Twenty-two were collected only in the cotton field; 16, only in the pasture.
Exline, Harriet   +2 more
core   +2 more sources

Spinal Cord Infarction Versus Idiopathic Transverse Myelitis: Clinical, Radiological, and Functional Insights From a Retrospective Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Spinal cord infarction (SCI) is a rare but devastating myelopathy, characterized by a high disability rate and an unfavorable prognosis. It has often been underdiagnosed and misdiagnosed as idiopathic transverse myelitis (ITM). This study aimed to describe the clinical features, radiological biomarkers, treatments, and functional ...
Zeqiang Ji   +13 more
wiley   +1 more source

Culling and mortality of dairy cows: why it happens and how it can be mitigated [version 2; peer review: 2 approved]

open access: yesF1000Research, 2022
The United Nations estimates that the global population will total 9.7 billion in 2050. Rapid population growth pose a significant obstacle to achieving the Sustainable Development Goals, particularly eradicating hunger and poverty.
Diniso Simamkele Yanga   +1 more
doaj   +1 more source

Pasture Productivity Trial [PDF]

open access: yes, 2017
Pasture is an essential component of the ration on organic dairy farms. Productivity of pastures is key to ensure the cattle have a plentiful source of high quality feed during the entire grazing season.
Cummings, Erica   +4 more
core   +1 more source

Innate Immune Reprogramming Mediated by Endogenous Retroelement Dysregulation Drives Multiple Sclerosis Progression

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
Epigenetic reprogramming in hematopoietic stem and progenitor cells (HSPCs) and downstream myeloid cells, mediated by H3.3 downregulation and endogenous retroelement (ERE) overexpression, contributes to the progression of multiple sclerosis (MS). ABSTRACT Background Skewed myelopoiesis in the bone marrow has been identified as a key driver of multiple ...
Li‐Mei Xiao   +6 more
wiley   +1 more source

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