Results 121 to 130 of about 198,322 (304)

Natural Frequencies of Levodopa‐Induced Dyskinesia in Parkinson's Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Abnormal involuntary movements, known as dyskinesias, are common complications of levodopa treatment in patients with Parkinson's disease and can significantly impair quality of life. The underlying pathophysiology remains unclear, and current therapeutic options are limited.
Ioannis U. Isaias   +3 more
wiley   +1 more source

Disease Course After Anti‐CD20 Discontinuation in Secondary Progressive Multiple Sclerosis—A Multicenter Long‐Term Longitudinal Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To describe long‐term outcomes after anti‐CD20 discontinuation in selected patients with secondary progressive multiple sclerosis (SPMS) who remained without subsequent disease‐modifying therapy (DMT). Methods We retrospectively analyzed data from four centers in Austria and Switzerland.
Ferdinand Otto   +12 more
wiley   +1 more source

Pat Williams Interview, 1989 [PDF]

open access: yes, 1989
Pat Williams discusses Mike Mansfield’s legacy as a U.S. Representative, Senator, and Ambassador to Japan. He talks about the precedent that Mike Mansfield’s tenure as a U.S.
Williams, Pat
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Significance of Whole Blood Viscosity in Acute Ischemic Stroke

open access: yesLife
The paper provides a comprehensive review of the relationship between whole blood viscosity (WBV) and acute ischemic stroke (AIS) concerning AIS risk and type, and its treatment and prognosis.
Irena Velcheva   +2 more
doaj   +1 more source

Intracerebral Hemorrhage Induces Monocyte TNF Signaling in Patients That Is Suppressed by BAF312

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Intracerebral hemorrhage (ICH) causes high morbidity and mortality, with neurotoxic inflammation driven by infiltrating monocytes. This study is an in‐depth longitudinal examination of the immune response during the first week of ICH in the presence and absence of the immunomodulatory drug BAF312 (Siponimod).
Jonathan Howard DeLong   +10 more
wiley   +1 more source

Pat Morse Interview, June 2011 [PDF]

open access: yes, 2011
This is Pat Morse\u27s second interview on her memories about growing up in the Cuyahoga ...

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Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem   +9 more
wiley   +1 more source

Interview with Pat Cariaga [PDF]

open access: yes, 2009
My interview concerns the life of Pat Simon Cariaga, as well as her relation to Chinatown in Salinas, California. Pat’s father was Filipino and her mother was German, and divorced when Pat was very young.
Cariaga, Pat   +1 more
core   +1 more source

“Low‐Positive” MOG‐IgG Cases Among Adults With a First Event Suggestive of Multiple Sclerosis

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the prevalence and clinical characteristics of patients with “low‐positive” (LP) MOG‐IgG (titres 1:160–1:320) among adults with a first demyelinating event (FDE) suggestive of multiple sclerosis (MS). Methods From the Barcelona CIS inception cohort, we included adult patients with serum collected ≤ 6 months from the FDE.
Javier Villacieros‐Álvarez   +29 more
wiley   +1 more source

Hour-long interview with Alan Macfarlane for Anthropological Ancestors video archive. [PDF]

open access: yes
Interview of Pat Caplan by Alan Macfarlane. Filmed by Sarah Harrison, 18th January 2004 Pat Caplan describes the setting up of the anthropology department at Goldsmith's College, University of ...
Caplan, Pat
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