Results 41 to 50 of about 6,234,956 (350)

Pat

, 1879
Location of original: Library of the National Folklore Collection, John Henry Newman Building, University College Dublin.
Hamilton, Edwin, 1849-1919, O'Hea, John Fergus, Swan, W. P., Fitzpatrick, Thomas, 1860-1912   +3 more
openaire   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

FEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi, Pilar Samperio Ventayol, Natalie Burkard, Nicolas Schlegel, Carmen Aguilar, Sina Bartfeld   +5 more
wiley   +1 more source

pat‐geom: A software package for the analysis of animal patterns

Methods in Ecology and Evolution, 2019
Colour patterns often influence how animals interact with one another, but the ability of researchers to quantify pattern per se is hampered by a lack of easily accessible and user‐friendly measurement software packages.
Ian Z. W. Chan, M. Stevens, P. Todd
semanticscholar   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

FEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace, Alyssa Borges, Charles Arnaud, Tove Karlsson, Nina K. Bröker, Stefanie Barbirz, Marta Bally   +6 more
wiley   +1 more source

Are impermeable curtains necessary for a groundwater contaminant remediation project?

Journal of Groundwater Science and Engineering
Constructing impermeable curtains to contain contaminant in aquifers is a costly and complex process that can impact the structure integrity of aquifer systems. Are impermeable curtains necessary for a groundwater contaminant remediation project?
Ming Guo, Yun Yang, Qian-kun Luo, Ying-chun Li, Hai-chun Ma, Jia-zhong Qian   +5 more
doaj   +1 more source

Common Statin Intolerance Variants in ABCB1 and LILRB5 Show Synergistic Effects on Statin Response: An Observational Study Using Electronic Health Records

Frontiers in Genetics, 2021
Background: Statin intolerance impacts approximately 10% of statin users, with side effects ranging from mild myalgia to extreme intolerance resulting in myopathy and rhabdomyolysis.
Alaa’ Lutfi Melhem, Mehul Kumar Chourasia, Margherita Bigossi, Margherita Bigossi, Cyrielle Maroteau, Alasdair Taylor, Roberto Pola, Adem Y. Dawed, Aleksi Tornio, Aleksi Tornio, Colin N. A. Palmer, Moneeza K. Siddiqui   +11 more
doaj   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source

The GTB and PAT tools

Electronic Notes in Theoretical Computer Science, 2004
AbstractThe Grammar Tool Box is a toolset for manipulating Context Free Grammars and objects asso- ciated with them such as parsers, languages and derivations. GTB has three main rôles: as a pedagogic tool; as an experimental platform for novel algorithms and representations; and as a production tool for translator front end generation.
Adrian Johnstone, Elizabeth Scott, Giorgios Economopoulos   +2 more
openaire   +1 more source

Accelerating Biologics Manufacturing by Modeling or: Is Approval under the QbD and PAT Approaches Demanded by Authorities Acceptable Without a Digital-Twin?

Processes, 2019
Innovative biologics, including cell therapeutics, virus-like particles, exosomes,recombinant proteins, and peptides, seem likely to substitute monoclonal antibodies as the maintherapeutic entities in manufacturing over the next decades.
S. Zobel‐Roos, A. Schmidt, F. Mestmäcker, M. Mouellef, M. Huter, L. Uhlenbrock, M. Kornecki, L. Lohmann, R. Ditz, J. Strube   +9 more
semanticscholar   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source