Results 61 to 70 of about 6,234,956 (350)

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Pengaruh Harga, Kualitas Pelayanan, dan Inovasi Desain Terhadap Loyalitas Pembelian Merk Minorfighters

open access: yesJKBM (Jurnal Konsep Bisnis dan Manajemen), 2019
The increasing growth of retail products in Indonesia has led to the increasing level of competition in the retail business faced by domestic products. The usefulness of this research is to detect the influence of price levels, service quality and design
Roymon Panjaitan
doaj   +1 more source

Association between periodontal disease and pericardial adipose tissue in patients with cardiovascular disease

open access: yesAmerican Heart Journal Plus, 2023
Background: Periodontal disease (PD) is associated with an increased risk of cardiovascular disease (CVD). Pericardial adipose tissue (PAT) is known as a marker of progressive CVD.
Yoshinori Kanno   +16 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

Development of PCR screening assays focused on gene-coding sequences for GMO detection

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2018
Description of the subject. This paper describes the development, evaluation and limitations of screening PCR assays based on genes and for use in GMO detection. Objectives.
Debode, F., Janssen, E., Berben, G.
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Avaliação dos parâmetros nutricionais de refeições transportadas em um restaurante comercial na cidade de Alfenas-MG

open access: yesRevista Brasileira de Obesidade, Nutrição e Emagrecimento, 2020
Atualmente o setor de serviços alimentícios possui um papel muito importante com a economia do Brasil. Dentre os diversos estímulos desse setor, foi instituído o Programa de Alimentação do Trabalhador (PAT) em 1976 e decretado em 1991.
Gabriel Abreu Alvarenga Maciel   +2 more
doaj  

Evaluation of Acridine Orange Staining for a Semi-Automated Urinalysis Microscopic Examination at the Point-of-Care

open access: yesDiagnostics, 2019
A urinary tract infection (UTI) can be diagnosed via urinalysis, consisting of a dipstick test and manual microscopic examination. Point-of-care (POC) image-based systems have been designed to automate the microscopic examination for low-volume ...
Amy J. Powless   +5 more
doaj   +1 more source

Validation of the Spanish Version of the Psychosocial Assessment Tool (PAT) in Pediatric Cancer

open access: yesJournal of Pediatric Psychology, 2018
Objective Family psychosocial risk screening is an important initial step in delivering evidence-based care and in addressing health disparities. There is currently no validated measure of family psychosocial risk in Spanish.
A. Kazak   +7 more
semanticscholar   +1 more source

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