Results 71 to 80 of about 6,234,956 (350)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Pemodelan Implementasi Open Access Repository Menggunakan Eprints Software di IAIN Curup

Khizanah al-Hikmah, 2020
Pentingnya proses pengarsipan secara digital di IAIN Curup yang diawali dengan proses pengumpulan, pemeliharaan serta diseminasi pengetahuan karya ilmiah melalui proses penyebaran informasi yang direncanakan, diarahkan dan dikelola serta direpositorikan ...
Wandi Syahindra, Murlena Murlena, Hasni Hartati   +2 more
doaj   +1 more source

Finding novel vulnerabilities of hypomorphic BRCA1 alleles

Molecular Oncology, EarlyView.
Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder, Klaas de Lint, Hồ Mỹ Phúc Võ, Mariana M. Góis, Rosalie A. Kampen, Marta San Martin Alonso, Ilse Nootenboom, Veronica Garzero, Tiemen J. Wendel, Rob M. F. Wolthuis, Sylvie M. Noordermeer   +10 more
wiley   +1 more source

Pat Boone

, 1977
Pat Boone, nationally known singer and actor, at a Christian ...

core   +1 more source

Patient perspectives on the role of orthopedic nurse practitioners: a cross-sectional study

BMC Nursing
Background The inclusion of nurse practitioners (NPs) specializing in orthopedics shows potential for improving the quality of care for orthopedic patients.
Merav Ben Natan, May Revach, Or Sade, Yaniv Yonay, Yaron Berkovich   +4 more
doaj   +1 more source

The Scholarship of Teaching and Learning as a Subversive Activity

Teaching & Learning Inquiry: The ISSOTL Journal, 2016
One of the most serious challenges facing higher education today is the erosion of academic culture—a declining sense that faculty form a community whose members reflect, deliberate, and make decisions together in the name of a shared educational vision.
David L. Boose, Pat Hutchings
doaj   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

PENGEMBANGAN SISTEM INFORMASI AKAD MUDHĀRABAH BANK SYARIAH BERBASIS DSS DENGAN MENGGUNAKAN METODE AHP

Economica: Jurnal Ekonomi Islam, 2016
This research aims to develop a scoring system awarding financial cooperation that existed at Syariah Banking using various contract in it. The development of this system will replace the performance of the analytical assess and decide on the granting of
Setyo Budi Hartono, Jarot Dian Susatyono, Abdul Kholiq   +2 more
doaj   +1 more source

Family psychosocial risk screening guided by the Pediatric Psychosocial Preventative Health Model (PPPHM) using the Psychosocial Assessment Tool (PAT)

Acta oncologica, 2015
Background. Although families of children with cancer and other serious medical conditions have documented psychosocial needs, the systematic identification of needs and delivery of evidence-based care remain challenges. Screening for multifaceted family
A. Kazak, S. Schneider, Stephen DiDonato, A. Pai   +3 more
semanticscholar   +1 more source

Recording of interview with Pat Parry (Vol.1)

, 2006
Pat Parry is a professor of English at Alfred University, NY. Parry met Nouwen while on sabbatical from Alfred University at Yale Divinity School and developed a lifelong friendship with him.1 (out of 2) audio cassettes (1 hr., 22 mins.)Title based on ...
Parry, Pat
core