Results 91 to 100 of about 6,234,956 (350)

GRP78-directed immunotherapy in relapsed or refractory multiple myeloma - results from a phase 1 trial with the monoclonal immunoglobulin M antibody PAT-SM6

Haematologica, 2015
The primary objective of this phase 1 study was to evaluate the safety and tolerability of the anti-glucose regulated protein 78 monoclonal immunoglobulin M antibody PAT-SM6 in subjects with relapsed or refractory multiple myeloma.
L. Rasche, J. Duell, Inês C Castro, V. Dubljevic, M. Chatterjee, S. Knop, F. Hensel, A. Rosenwald, H. Einsele, M. Topp, S. Brändlein   +10 more
semanticscholar   +1 more source

Decreased cold‐sensing function of the transient receptor potential channel TRPM8 from tailed amphibians

FEBS Open Bio, EarlyView.
Despite frogs avoiding low temperatures, examination of four salamander species revealed that none avoided cold and all possessed cold tolerance. Functional analysis of TRPM8, a cold sensor, showed that all salamander TRPM8s had lost their cold sensitivity.
Tadahiro Sawao, Daiki Kobayashi, Shogo Hori, Osamu Saitoh   +3 more
wiley   +1 more source

Measurement uncertainty analysis of single-use flow sensors

Frontiers in Bioengineering and Biotechnology
The increased application of single-use (SU) equipment and sensor technology in biopharma and bioprocesses has a significant impact on development and production.
Niclas Ludolph, Julian Haller, Andreas Prediger   +2 more
doaj   +1 more source

“USE OF SOCIAL NETWORK ANALYSIS AS A STRATEGY FOR E-COMMERCE RECOMMENDATIONS”

Simetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2019
Agen Recommender sedang banyak digunakan oleh bisnis E-commerce untuk membantu pelanggan mengambil keputusan dari sejumlah besar pilihan. Untuk meningkatkan kinerja agen rekomendasi, tiga pendekatan utama (pendekatan berbasis konten, pendekatan ...
Daniel Adi Setya Rahardjo
doaj   +1 more source

PAT-seq: a method to study the integration of 3′-UTR dynamics with gene expression in the eukaryotic transcriptome

RNA: A publication of the RNA Society, 2015
A major objective of systems biology is to quantitatively integrate multiple parameters from genome-wide measurements. To integrate gene expression with dynamics in poly(A) tail length and adenylation site, we developed a targeted next-generation ...
P. Harrison, David R. Powell, J. Clancy, T. Preiss, P. Boag, Ana Traven, T. Seemann, T. Beilharz   +7 more
semanticscholar   +1 more source

Pat Farmer

, 1990
"Pat Farmer now (McFayden) December 1941 "Plane"."Date ...
Farmer, Pat
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Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Pat Clements

, 1976
Pat Clements, a Bradenton Herald employee in the composing ...

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Why human connection is the true metric of research success

FEBS Open Bio, EarlyView.
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan, Mattias Wei Ren Kon, Xavier Coumoul, Fun Man Fung   +3 more
wiley   +1 more source

Pat Clements

, 1979
Pat Clements, Bradenton Herald employee of the ...

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