Results 81 to 90 of about 1,394,136 (302)

Phonon-assisted tunneling in asymmetric resonant tunneling structures

, 1998
Based on the dielectric continuum model, we calculated the phonon assisted tunneling (PAT) current of general double barrier resonant tunneling structures (DBRTSs) including both symmetric and antisymmetric ones. The results indicate that the four higher
Ers A, Jun-jie Shi, P. R. China, Shao-hua Pan A   +3 more
core   +2 more sources

Endothelial function assessment in atherosclerosis: Comparison of brachial artery flow‑mediated vasodilation and peripheral arterial tonometry [PDF]

, 2013
INTRODUCTION Endothelial dysfunction, characterized by the loss of nitric oxide bioavailability, is a key element in the pathogenesis of atherosclerosis and an important prognostic factor in cardiovascular diseases. Therefore, the development of reliable,
Czesnikiewicz-Guzik, Marta, Guzik, Tomasz J., Ignacak, Adam, Jasiewicz‑Honkisz, Barbara, Matusik, Paweł, Nowakowski, Daniel, Osmenda, Grzegorz, Wilk, Grzegorz   +7 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Measurement uncertainty analysis of single-use flow sensors

Frontiers in Bioengineering and Biotechnology
The increased application of single-use (SU) equipment and sensor technology in biopharma and bioprocesses has a significant impact on development and production.
Niclas Ludolph, Julian Haller, Andreas Prediger   +2 more
doaj   +1 more source

“USE OF SOCIAL NETWORK ANALYSIS AS A STRATEGY FOR E-COMMERCE RECOMMENDATIONS”

Simetris: Jurnal Teknik Mesin, Elektro dan Ilmu Komputer, 2019
Agen Recommender sedang banyak digunakan oleh bisnis E-commerce untuk membantu pelanggan mengambil keputusan dari sejumlah besar pilihan. Untuk meningkatkan kinerja agen rekomendasi, tiga pendekatan utama (pendekatan berbasis konten, pendekatan ...
Daniel Adi Setya Rahardjo
doaj   +1 more source

Surgical complications in human orthotopic liver transplantation. [PDF]

, 1987
Between March 1, 1980 and December 31, 1984, 393 orthotopic liver transplantations (OLT) were performed in 313 consecutive recipients. Technical complications were responsible for a substantial morbidity (41/393 allograft loss--10.4%) and mortality (26 ...
Gordon, RD, Iwatsuki, S, Lerut, J, Starzl, TE   +3 more
core  

Screening and epitope characterization of Nidogen‐2‐specific nanobodies

FEBS Open Bio, EarlyView.
Camel immunization and phage display were employed to generate high‐affinity VHH nanobodies against Nidogen‐2. After library construction, biopanning, ELISA screening, sequencing, and recombinant expression, selected nanobodies were purified and characterized, leading to the preliminary exploration of a nanobody‐based sandwich ELISA for specific ...
Jianchuan Wen, Qianqian Cui, Zhongyun Lan, Yingjun Wang, Shuaiying Zhao, Wenxuan Feng, Yunfeng Liu, Qiting Huang, Dongna Zhang, Jianfeng Xu   +9 more
wiley   +1 more source

Iron homeostasis disruption and lipid peroxidation in skeletal muscle during short‐term immobilization

FEBS Open Bio, EarlyView.
14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa, Kazuhiko Higashida, Naoya Nakai   +2 more
wiley   +1 more source

Implementing an ICT centre for school and community [PDF]

, 2009
The British Government, in parallel to the move to e-government, has introduced various strategies to embed ICT within secondary-school learning. One strand of this approach has been the establishment of City Learning Centres (CLCs), state-of-the art ICT-
Gannon-Leary, Pat
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