Results 81 to 90 of about 198,322 (304)

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

FEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill, Hassan Yousef Othman AlMuallim, Elouisa Maddock, Carl Hobbs, Earl Clarke, Maria B. Goncalves, Jonathan P. T. Corcoran   +6 more
wiley   +1 more source

Correspondence from Pat Shankland [PDF]

, 1945
Digital copies were created from a selection of items in the original hard copy Albert Coates collection (PDV 4) held in DOMUS in the Stellenbosch University Music Library.Letter from Pat [Shankland] regarding the 'Zarathustra'
Coates, Albert, 1882-1953
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Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Munson, Pat Oral History [PDF]

, 1990
Recorded oral history of Pat Munson and his looking back and recalling people and events he experienced in Monroe ...
Munson, Pat
core  

From patient advocacy to patient‐driven research: Building active partnerships beginning at the bench to reach the bedside

FEBS Open Bio, EarlyView.
Research is strongest when conducted alongside patients, not just about them. Patient research organizations help integrate patient perspectives into research priorities, study design, and scientific meetings, leading to meaningful patient outcomes and development of relevant therapies.
Jenica H. Kakadia, Rachel Heilmann, Maximiliano Barrientos, Laura MacNeill, Ingrid Vallee, Sarah K. Schultz, Patrick O'Donoghue, Angelica A. Moresco, Victoria M. Siu, Ilka U. Heinemann   +9 more
wiley   +1 more source

Pat Harden [PDF]

, 2010
Pat Harden, environmentalist and Founder of Friends of the Wekiva River, interviewed by Caleb Fontanez on November 15 ...
Harden, Pat, Fontanez, Caleb
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Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Budweiser Clydesdales, Pat [PDF]

, 2002
Budweiser Clydesdales, Pat at Bud World at Gallivan Center during the 2002 Winter ...
Scott, Pat
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Dampak Proses Politik dan Konsekuensi Ekonomi dalam Pembentukan Suatu Standar

Journal of Accounting and Investment, 2016
Standard setters should consider the possibility of the political process and economic consequences in making standard. The underlying reason is to reduce the presence of the injured party.
Aida Ainul Mardiyah
doaj  

Solid Subtype of Papillary Thyroid Carcinoma: A Case Series Highlighting Aggressive Features

Clinical Case Reports
Papillary thyroid carcinoma (PTC) is the most common malignant thyroid neoplasm. Its solid/trabecular subtype (STPTC) is rare, and its aggressiveness remains controversial.
Rafael Castellanos Bueno, Gabriela Almeyda Carreño, Diana Carolina Vergara Arenas, Laura Yibeth Esteban Badillo, Ernesto García Ayala   +4 more
doaj   +1 more source