Results 111 to 120 of about 326,331 (291)

Modern tendencies in the development of the patch-clamp technique: new opportunities for neuropharmacology and neurobiology

open access: yesАнналы клинической и экспериментальной неврологии, 2017
The patch-clamp (PC) technique is the gold standard in studyingprocesses that occur on the membranes of excitable cells,both in the physiological condition and in pathology.
A. N. Shuvaev   +4 more
doaj   +1 more source

NOVEL TECHNIQUES FOR IN VIVO CHARACTERIZATION OF SHORT PEPTIDES AND PROTEINS IN MEMBRANE PERMEABILIZATION AND SIGNAL TRANSDUCTION [PDF]

open access: yes, 2012
My scientific interest is focused on the field of cellular electrical activity, ranging from the study of intracellular enzymatic processes to the characterization of new generation of drugs.
Aquila, Marco
core  

In‐House Manufacturing of 3D ECM Culture Chips via Vacuum Thermoforming for Enhanced Imaging Applications

open access: yesAdvanced Materials Technologies, EarlyView.
Desktop vacuum thermoforming enables rapid, low‐cost fabrication of 96‐channel polystyrene culture chips with very thin imaging interfaces. The resulting platform supports cell lines, primary cells, and patient‐derived organoids, and enables high‐resolution confocal microscopy and single‐cell visualization, providing an accessible approach for advanced
Aleksandra Fomina   +5 more
wiley   +1 more source

Liquid Crystal Elastomer Actuator Matrix for Large Area Applications

open access: yesAdvanced Materials Technologies, EarlyView.
A scalable approach is used to manufacture a digitally‐controllable, 2D 5 × 5 actuator matrix. The elements of the matrix are produced by direct ink writing of a liquid crystal elastomer ‘artificial muscle’ on large‐area flexible thin‐film heaters. In optimizing the low‐power actuators, multiple heater designs and substrate materials are investigated ...
Giulia Spallanzani   +5 more
wiley   +1 more source

Liquid Metal Resistive Sensing Architectures for Measuring Diaphragm Strain Responses on Obstructed Surfaces

open access: yesAdvanced Materials Technologies, EarlyView.
A liquid metal‐based strain‐sensing architecture to measure the deformation of a circular diaphragm against obstructed surfaces is formulated using finite element modeling and confocal imaging to establish the mechanical framework and is utilized to control diaphragm‐induced confinement on a bead array, as validated by biomolecular loading level ...
Abdullah‐Bin Siddique   +4 more
wiley   +1 more source

Planar patch clamp for neuronal networks - Considerations and future perspectives

open access: yes, 2014
The patch-clamp technique is generally accepted as the gold standard for studying ion channel activity allowing investigators to either "clamp" membrane voltage and directly measure transmembrane currents through ion channels, or to passively monitor ...
Bosca, Alessandro   +5 more
core   +1 more source

Elimination of Necking and Aspect Ratio Dependence in Uniaxial Actuators by Continuous Fiber Reinforcement

open access: yesAdvanced Robotics Research, EarlyView.
A novel carbon fiber reinforcement for dielectric elastomer actuators enhances actuation force while decoupling electromechanical performance from the actuator's aspect ratio. Unlike conventional fiber reinforcements, it enables a uniform planar stretch state along the entire actuator.
Markus Koenigsdorff   +8 more
wiley   +1 more source

Patch Clamp Technique

open access: yesEquilibrium Research, 2008
The patch clamp technique enables the analyses of various ion channel characteristics of individual cells in vitro. The most important difference from previous techniques is that the microelectrode (pipette) is firmly attached to the cell surface instead of being inserted into the cells, and the so-called "giga-ohm seal" is attained. Usually, the whole
  +6 more sources

A Proof‐of‐Concept Assessment of a Novel Wearable Eyelid Muscle Device: A Pre‐Clinical Animal Cadaver Study for Eyelid Closure Restoration

open access: yesAdvanced Robotics Research, EarlyView.
This article introduces a soft wearable eyelid sling device incorporating a hydraulic soft artificial muscle (SAM) for achieving complete closure of an eyelid. The SAM is driven by a cam mechanism that provides a displacement profile closely matched with those of a healthy eyelid.
Patrick Pruscino   +7 more
wiley   +1 more source

Clamp Tie and Surgery Bucket Module: How to Build

open access: yes, 2018
"Clamp and Tie Module Goal: residents should be able to pass a silk tie atraumatically around a clamped structure and tie into a hole. Clamp and Tie Module Instructions: (Can be completed solo or with partner): 1.
Peter Bartline MD; Ruth Braga MSN; William Peche MD; Daniel Vargo MD
core  

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