Results 101 to 110 of about 741,076 (339)

Transfinite Patches for Isogeometric Analysis

open access: yesMathematics
This paper extends the well-known transfinite interpolation formula, which was developed in late sixties by the applied mathematician William Gordon at the premises of General Motors as an extension of the pre-existed Coons interpolation formula. Here, a conjecture is formulated, which claims that the meaning of the involved blending functions can be ...
openaire   +2 more sources

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

open access: yesMolecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son   +13 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

Understanding the Patch Dynamics of a few Homogenous and Heterogenous Vegetational Patches [PDF]

open access: yesNature Environment and Pollution Technology
Variations in size and shape distinguish vegetation patches across different ecosystems. Nonetheless, recent research highlights notable parallels in the dynamics of these patches and the mechanisms governing their formation and persistence.
Rekha G. Dhammar, Kunal N. Odedra and B. A. Jadeja
doaj   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

open access: yesMolecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto   +8 more
wiley   +1 more source

Acceptability of antipsychotic transdermal patch for acute schizophrenia: a systematic review and meta‐analysis [PDF]

open access: bronze, 2023
Taro Kishi   +5 more
openalex   +1 more source

Analysis of Multilayer Patch Antenna [PDF]

open access: yesInternational Journal of Scientific Research in Physics and Applied Sciences, 2019
P. Jothilakshmi   +2 more
openaire   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

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