Results 91 to 100 of about 740,828 (291)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Cantilever Plate Mid-Span Patch Method for Dynamically Testing the In-Plane Poisson's Ratio of Oriented Strand Board

BioResources, 2023
A cantilever plate span-to-span patch method was proposed and demonstrated for dynamic testing of OSB Poisson's ratio with high testing accuracy, simplicity, ease of implementation, and effectiveness.
Yuying Zou, Zheng Wang, Yifan Zhang, Yuhao Zhou, Zhaoyu Shen   +4 more
doaj   +2 more sources

Exploring the potential of tomato juice (Solanum lycopersicum L.) patch for tooth bleaching [PDF]

Journal of Dental Research, Dental Clinics, Dental Prospects
Background. Tomato, renowned for its tooth-whitening properties due to its hydrogen peroxide and peroxidase enzyme content, requires formulation for enhanced applicability.
Laifa Annisa Hendarmin, Berliana Novianita, Yuni Anggraeni, Khairunissa Febriyanti   +3 more
doaj   +1 more source

Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin

Molecular Oncology, EarlyView.
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla, Jan Kosla, Magdalena Prechova, Lukas Frick, Patricia Bortel, Yasmin Borutzki, Andrea Bileck, Christopher Gerner, Samuel M. Meier‐Menches, Selma Osmanagic‐Myers, Martin Gregor   +10 more
wiley   +1 more source

Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers

Drug Design, Development and Therapy, 2015
Yo Han Kim,1 Hee Youn Choi,1 Hyeong-Seok Lim,1 Shi Hyang Lee,1 Hae Sun Jeon,1 Donghyun Hong,2 Seong Su Kim,2 Young Kweon Choi,2 Kyun-Seop Bae1 1Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical ...
Kim YH, Choi HY, Lim HS, Lee SH, Jeon HS, Hong D, Kim SS, Choi YK, Bae KS   +8 more
doaj  

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Sensitivity enhancement for moisture content detection using modified microstrip patch antennas

AIP Advances
A modified slotted microstrip patch sensor antenna has been developed for sensitivity enhancement to measure the moisture content of leaves. The design incorporates a rectangular slot positioned above the feed of a rectangular patch antenna.
Muhammad Talha Khan, Xian Qi Lin, Abid Muhammad Khan, Zhe Chen   +3 more
doaj   +1 more source

On line estimation of rolling resistance for intelligent tires [PDF]

, 2016
The analysis of a rolling tire is a complex problem of nonlinear elasticity. Although in the technical literature some tire models have been presented, the phenomena involved in the tire rolling are far to be completely understood.
CARCATERRA, Antonio, PEPE, GIANLUCA, ROVERI, NICOLA   +2 more
core  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Effect of Utility Cut Patching on Pavement Deterioration

Journal of King Saud University: Engineering Sciences, 1992
Utility Cut Patching (UCP) is a major cause of pavement deterioration in city streets. The streets of the city of Riyadh are no exception. A study was undertaken to investigate factors related to UCP and possibly contributing to pavement deterioration ...
Abdul-Rahman S. Al-Suhaibani, Bassam A. Anani, Ibrahim A. AlKharashi   +2 more
doaj   +1 more source