Results 131 to 140 of about 289,898 (312)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Behavior of RC beams patch repaired and strengthened with FRP composites : a numerical study

, 2014
Includes bibliographical references.Reinforced concrete (RC) beams get deteriorated and become deficient mainly due to corrosion of steel reinforcements, poor maintenance and design, earthquakes and aging.
Mundeli, Salathiel
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Nonlinear solid mechanics analysis using the parallel selective element-free Galerkin method [PDF]

, 2013
A variety of meshless methods have been developed in the last fifteen years with an intention to solve practical engineering problems, but are limited to small academic problems due to associated high computational cost as compared to the standard finite
ULLAH, ZAHUR
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Appendix C. Analysis of asymmetric patch size.

, 2016
Analysis of asymmetric patch ...
Nicolas Mouquet (143960), Dominique Gravel (98797), Frédéric Guichard (177600), Michel Loreau (60807)   +3 more
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Finite Elements Analysis of a Butterfly-Shaped Composite patch Repair and its Comparison to the Usual Shapes

Journal of Materials and Engineering Structures, 2017
A 3-D finite element analysis was conducted on a thin aluminum plate with a 45 ° inclined central crack.  A modeling of the bonding repair with composite patch of different shapes was carried out. In addition to the patch shapes studied in the literature,
ElHadj BESSEGHIER, Abedlkader DJEBLI, Mostefa BENDOUBA, Abdelkrim AID   +3 more
doaj  

A textile-based platform for real-time sweat collection and analysis [PDF]

, 2009
The ability to perform real-time chemical measurements of body fluids is an exciting concept for the healthcare sector and the sports industry. This work is part of the BIOTEX project, an EU FP6 project which involved the development of textile-based ...
Coyle, Shirley, Lau, King-Tong, Taccini, Nicola, Paradiso, Rita, Chuzel, Cyril, Diamond, Dermot   +5 more
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Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Is the Capsaicin 179 mg (8% w/w) Cutaneous Patch an Appropriate Treatment Option for Older Patients with Peripheral Neuropathic Pain?

Journal of Pain Research
Gisèle Pickering,1 Sylvia Engelen,2 Maria Stupar,2 Hervé Ganry,3 Mariëlle Eerdekens2 1Faculty of Medicine Inserm 1107, Clinical Pharmacology Centre, CPC/CIC Inserm 1405 University Hospital, Clermont-Ferrand, France; 2Grünenthal GmbH, Aachen, Germany ...
Pickering G, Engelen S, Stupar M, Ganry H, Eerdekens M   +4 more
doaj  

Stack patch antenna analysis.

, 2021
Diplomski rad analizira stacked patch antene koje se koriste umjesto običnih jednoslojnih mikrotrakastih antena za proširenje frekvencijskog pojasa rada.
Radoš, Marko
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