Isogeometric analysis for multi-patch structured Kirchhoff-Love shells [PDF]
, 2022 Andrea Farahat +3 more
openalex +1 more source
Effect of 3D Roughness Patch on Instability Amplification in a Supersonic Boundary Layer [PDF]
Surface roughness is known to have a substantial impact on the aerothermodynamic loading of high-speed vehicles, particularly via its influence on the laminar-turbulent transition process within the boundary layer.
Duan, Lian, Li, Fei, Paredes, Pedro
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Exploring the potential of tomato juice (Solanum lycopersicum L.) patch for tooth bleaching [PDF]
Journal of Dental Research, Dental Clinics, Dental ProspectsBackground. Tomato, renowned for its tooth-whitening properties due to its hydrogen peroxide and peroxidase enzyme content, requires formulation for enhanced applicability.
Laifa Annisa Hendarmin +3 more
doaj +1 more source
Design and Analysis of an Elliptical Edge with Pentagon Slot Patch Antenna for 5G Applications [PDF]
, 2022 Pendli Pradeep +2 more
openalex +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Single dose pharmacokinetics of the novel transdermal donepezil patch in healthy volunteers
Drug Design, Development and Therapy, 2015 Yo Han Kim,1 Hee Youn Choi,1 Hyeong-Seok Lim,1 Shi Hyang Lee,1 Hae Sun Jeon,1 Donghyun Hong,2 Seong Su Kim,2 Young Kweon Choi,2 Kyun-Seop Bae1 1Department of Clinical Pharmacology and Therapeutics, College of Medicine, University of Ulsan, Asan Medical ...
Kim YH +8 more
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Sensitivity enhancement for moisture content detection using modified microstrip patch antennas
AIP AdvancesA modified slotted microstrip patch sensor antenna has been developed for sensitivity enhancement to measure the moisture content of leaves. The design incorporates a rectangular slot positioned above the feed of a rectangular patch antenna.
Muhammad Talha Khan +3 more
doaj +1 more source
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source