Results 61 to 70 of about 740,828 (291)

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

sMRI-PatchNet: A Novel Efficient Explainable Patch-Based Deep Learning Network for Alzheimer’s Disease Diagnosis With Structural MRI

open access: yesIEEE Access, 2023
Structural magnetic resonance imaging (sMRI) can identify subtle brain changes due to its high contrast for soft tissues and high spatial resolution. It has been widely used in diagnosing neurological brain diseases, such as Alzheimer’s disease ...
Xin Zhang   +5 more
doaj   +1 more source

Detecting Repeating Objects Using Patch Correlation Analysis [PDF]

open access: yes2016 IEEE Conference on Computer Vision and Pattern Recognition (CVPR), 2016
In this paper we describe a new method for detecting and counting a repeating object in an image. While the method relies on a fairly sophisticated deformable part model, unlike existing techniques it estimates the model parameters in an unsupervised fashion thus alleviating the need for a user-annotated training data and avoiding the associated ...
Inbar Huberman, Raanan Fattal
openaire   +2 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Evaluation of spatial variability of the vegetation cover in arid and semiarid areas using measures of landscape ecology (Case study: Poshtkooh rangelands of Yazd) [PDF]

open access: yesمدیریت بیابان, 2016
Landscape ecology is one of theyoungest branches of ecology science, and especially deals on the study of landscape composition, structure and function.  Landscape elements are such as patches, corridors, matrixalong the border and ecotons.
Mohammad Ali Zare Chahouki   +2 more
doaj   +1 more source

Fully Portraying Patch Area Scaling with Resolution: An Analytics and Descriptive Statistics-Combined Approach

open access: yesLand, 2021
Scale effects are inherent in spatial analysis. Quantitative knowledge about them is necessary for properly interpreting and scaling analysis results.
Qianning Zhang, Zhu Xu
doaj   +1 more source

Image patch analysis of sunspots and active regions. I. Intrinsic dimension and correlation analysis

open access: yes, 2015
The flare-productivity of an active region is observed to be related to its spatial complexity. Mount Wilson or McIntosh sunspot classifications measure such complexity but in a categorical way, and may therefore not use all the information present in ...
De Visscher, Ruben   +5 more
core   +2 more sources

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Analysis of an air-spaced patch antenna near 1800 MHz [PDF]

open access: yes, 2011
Microstrip antennas are a type of printed antenna which consists of a patch on top of a grounded substrate. A major limitation for the performance of the patch antenna is the dielectric substrate.
Akouemo Kengmo Kenfack, Hermine Nathalie
core   +1 more source

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