Results 151 to 160 of about 214,804 (267)

Establishing an assay to evaluate d‐amino acid oxidase enzyme kinetics and inhibition using WST‐8 redox dye

FEBS Open Bio, EarlyView.
This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake, Yuki Enoki, Yuka Nakazawa, Kazuaki Taguchi, Kazuaki Matsumoto   +4 more
wiley   +1 more source

The Influence of Occupational Factors on Contact Dermatitis in Symptomatic Healthcare Workers: A Patch Test Study. [PDF]

Diseases
Ferrari C, Somma G, Giovinazzo V, Iarossi M, Treglia M, Pallocci M, Di Giampaolo L, Magrini A, Coppeta L.   +8 more
europepmc   +1 more source

Patch test of dental materials in Oral Lichen Planus with considering the role of saliva. [PDF]

Sci Rep, 2021
Agha-Hosseini F, Gholamrezayi E, Moosavi MS.   +2 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Epidemiological Comparative Study on Contact Sensitisations in Woodworkers With Occupational Dermatitis: Patch Test Data of the Information Network of Departments of Dermatology, 1999 to 2023. [PDF]

Contact Dermatitis
Heizmann L, Schubert S, Bauer A, Becker D, Brockow K, Dickel H, Kränke B, Lang C, Oppel E, Wagner N, Weisshaar E, Wilfinger D, Brans R, IVDK.   +13 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Patch test results to the Spanish baseline patch test series according to age groups: A multicentric prospective study from 2019 to 2023. [PDF]

Contact Dermatitis
Pesqué D, Planella-Fontanillas N, Borrego L, Sanz-Sánchez T, Zaragoza-Ninet V, Serra-Baldrich E, Miquel-Miquel FJ, Silvestre-Salvador JF, Córdoba-Guijarro S, Sánchez-Gilo A, Mercader-García P, Navarro-Triviño FJ, Ortiz-de-Frutos FJ, Tous-Romero F, Rodríguez-Serna M, Melé-Ninot G, Barrabés-Torrella C, Ruiz-González I, Pastor-Nieto MA, Carrascosa-Carrillo JM, Gómez-de-la-Fuente E, Sánchez-Pedreño-Guillén P, Sánchez-Pérez J, Pereyra-Rodríguez JJ, Gatica-Ortega ME, González-Pérez R, Pujol RM, Descalzo MÁG, García-Doval I, Giménez-Arnau AM.   +29 more
europepmc   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

Patch Test Results With the European Baseline Series, 2021/2022-Joint European Results of the ESSCA^A and the EBS^B Working Groups of the ESCD, and the GEIDAC^C. [PDF]

Contact Dermatitis
Uter W, Wilkinson SM, Aerts O, Bauer A, Borrego L, Brans R, Buhl T, Dickel H, Dugonik A, Filon FL, Arnau AG, Patruno C, Pónyai G, Gregoriou S, Schubert S, Simon D, Stingeni L, Valiukevičienė S, Weisshaar E, Werfel T, Gonçalo M, Schuttelaar MA, ESSCAA and EBSB ESCD Working Groups, and the GEIDACC .   +23 more
europepmc   +1 more source

YIPFα1A expression is regulated by multilayered molecular mechanisms

FEBS Open Bio, EarlyView.
YIPFα1A, a five‐pass Golgi protein, is regulated at multiple layers. (1) Rare‐codon enrichment drives translation‐coupled mRNA decay. (2) A proximal 3′‐UTR element stabilizes mRNA. (3) A distal 3′‐UTR element included by alternate poly(A) site usage represses translation, which can be overridden by the proximal 3′‐UTR element.
Tokio Takaji, Yurika Nakanishi, Nobuhiro Nakamura   +2 more
wiley   +1 more source