LVRF (lymphatic and vascular resistance factor) is a VEGFA splice variant upregulated in response to anti‐angiogenic therapy that fosters tumor adaptation through enhanced vascularization, lymphangiogenesis, and metastatic dissemination. Targeting LVRF with fully human neutralizing antibodies disrupts these processes and limits resistant tumor growth ...
Marion David +12 more
wiley +1 more source
The benefit of late patch test readings in corticosteroid allergy. [PDF]
Svendsen SV, Mortz CG.
europepmc +1 more source
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Contact Sensitization in Patients With Frontal Fibrosing Alopecia: Patch Test Results With an Extended Baseline Series in Consecutive Patients. [PDF]
Pastor-Nieto MA +11 more
europepmc +1 more source
Usefulness of dermoscopy in the evaluation of patch test reactions. [PDF]
Oppermann K, Cattani CAS, Bonamigo RR.
europepmc +1 more source
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan +8 more
wiley +1 more source
Evaluation of Artificial Intelligence-Assisted Diagnosis of Skin Erythema in a Patch Test. [PDF]
Kim S +9 more
europepmc +1 more source
Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley +1 more source
Patch Testing in Individuals With Diabetes Using Medical Devices. Part 2-Contact Allergy to Medical Device Allergens and New Patch Test Recommendations. [PDF]
Ulriksdotter J +5 more
europepmc +1 more source
Three Cases of Occupational Allergic Contact Dermatitis Where Causative Agents Were Identified Using Patch Test Panel S. [PDF]
Sasaki N +4 more
europepmc +1 more source

