Results 191 to 200 of about 16,362,977 (342)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Transcriptomic Analysis of Allergic Patch Test Reactions in Non-Atopic Patients: A Comparative Study Across Multiple Allergens. [PDF]

Allergy
Pesqué D, Andrades E, Berenguer-Molins P, Perera-Bel J, Clarós M, Bódalo-Torruella M, González-Farré M, Gallardo F, Pujol RM, Giménez-Arnau AM.   +9 more
europepmc   +1 more source

RIPK4 function interferes with melanoma cell adhesion and metastasis

Molecular Oncology, EarlyView.
RIPK4 promotes melanoma growth and spread. RIPK4 levels increase as skin lesions progress to melanoma. CRISPR/Cas9‐mediated deletion of RIPK4 causes melanoma cells to form less compact spheroids, reduces their migratory and invasive abilities and limits tumour growth and dissemination in mouse models.
Norbert Wronski, Sławomir Lasota, Ewelina Madej, Anna A. Brożyna, Małgorzata Szczygieł, Agnieszka Harazin‐Lechowska, Jan Czerbniak, Janusz Rys, Jaroslaw Czyz, Agnieszka Wolnicka‐Glubisz   +9 more
wiley   +1 more source

Prevalence of Contact Allergy to Propolis-Testing With Different Propolis Patch Test Materials. [PDF]

Contact Dermatitis
Antelmi A, Trave I, Gallo R, Cozzani E, Parodi A, Bruze M, Svedman C.   +6 more
europepmc   +1 more source

Patch test-relevant concentrations of metal salts cause localized cytotoxicity, including apoptosis, in skin ex vivo. [PDF]

Contact Dermatitis, 2021
Zhang Y, de Graaf NPJ, Veldhuizen R, Roffel S, Spiekstra SW, Rustemeyer T, Kleverlaan CJ, Feilzer AJ, Bontkes H, Deng D, Gibbs S.   +10 more
europepmc   +1 more source

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source

The Influence of Occupational Factors on Contact Dermatitis in Symptomatic Healthcare Workers: A Patch Test Study. [PDF]

Diseases
Ferrari C, Somma G, Giovinazzo V, Iarossi M, Treglia M, Pallocci M, Di Giampaolo L, Magrini A, Coppeta L.   +8 more
europepmc   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

Molecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen, Lucrezia De Santis, Bret M. Stephens, Vincent Bernard, Jörg C. Kalff, Lara Braun, Phillipp Leyendecker, Johannes Röttgen, Daniel Weissinger, Anirban Maitra, Paola A. Guerrero, Alexander Semaan   +11 more
wiley   +1 more source

Patch test results to the Spanish baseline patch test series according to age groups: A multicentric prospective study from 2019 to 2023. [PDF]

Contact Dermatitis
Pesqué D, Planella-Fontanillas N, Borrego L, Sanz-Sánchez T, Zaragoza-Ninet V, Serra-Baldrich E, Miquel-Miquel FJ, Silvestre-Salvador JF, Córdoba-Guijarro S, Sánchez-Gilo A, Mercader-García P, Navarro-Triviño FJ, Ortiz-de-Frutos FJ, Tous-Romero F, Rodríguez-Serna M, Melé-Ninot G, Barrabés-Torrella C, Ruiz-González I, Pastor-Nieto MA, Carrascosa-Carrillo JM, Gómez-de-la-Fuente E, Sánchez-Pedreño-Guillén P, Sánchez-Pérez J, Pereyra-Rodríguez JJ, Gatica-Ortega ME, González-Pérez R, Pujol RM, Descalzo MÁG, García-Doval I, Giménez-Arnau AM.   +29 more
europepmc   +1 more source

Exclusion of Disperse Orange 3 is possible from the textile dye mix present in the Swedish baseline patch test series. A study by the Swedish Contact Dermatitis Research Group. [PDF]

Contact Dermatitis, 2023
Isaksson M, Antelmi A, Dahlin J, Stenton J, Svedman C, Zimerson E, Glas B, Hagvall L, Lagrelius M, Löwnertz A, Malinauskiene L, Matura M, Bruze M.   +12 more
europepmc   +1 more source