Results 91 to 100 of about 14,105,689 (382)

Performance of an ablator for Space Shuttle inorbit repair in an arc-plasma airstream [PDF]

open access: yes
An ablator patch material performed well in an arc plasma environment simulating nominal Earth entry conditions for the Space Shuttle. Ablation tests using vacuum molded cones provided data to optimize the formulation of a two part polymer system for ...
Cuellar, M., Flowers, O., Stewart, D. A.
core   +1 more source

4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase in malaria parasites and enhances atovaquone efficacy

open access: yesFEBS Letters, EarlyView.
Atovaquone is an antimalarial requiring potentiation for sufficient efficacy. We pursued strategies to enhance its activity, showing that 4‐nitrobenzoate inhibits 4‐hydroxybenzoate polyprenyltransferase, decreasing ubiquinone biosynthesis. Since atovaquone competes with ubiquinol in mitochondria, 4‐nitrobenzoate facilitates its action, potentiating ...
Ignasi Bofill Verdaguer   +7 more
wiley   +1 more source

Linked dimers of the AAA+ ATPase Msp1 reveal energetic demands and mechanistic plasticity for substrate extraction from lipid bilayers

open access: yesFEBS Letters, EarlyView.
Cells must clear mislocalized or faulty proteins from membranes to survive. The AAA+ ATPase Msp1 performs this task, but dissecting how its six subunits work together is challenging. We engineered linked dimers with varied numbers of functional subunits to reveal how Msp1 subunits cooperate and use energy to extract proteins from the lipid bilayer ...
Deepika Gaur   +5 more
wiley   +1 more source

Stamping a case of cutaneous adverse drug reaction: Proving beyond causality assessment

open access: yesIndian Journal of Dermatology, 2018
Different types of skin testing with a suspected drug have been reported to be helpful in determining the cause of cutaneous adverse drug reactions (CADRs).
Sudip Das   +3 more
doaj   +1 more source

Construction and test of a dual patch multi- element radiant cooler Quarterly report, 17 Dec. 1970 - 17 Mar. 1971 [PDF]

open access: yes
Vibration tests on dual patch of radiant cooling apparatus, and emissivity and reflectance analysis of cones in radiative heat transfer ...
Annable, R. V.
core   +1 more source

A finite element method by patch reconstruction for the Stokes problem using mixed formulations

open access: yes, 2019
In this paper, we develop a patch reconstruction finite element method for the Stokes problem. The weak formulation of the interior penalty discontinuous Galerkin is employed.
Li, Ruo   +3 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Epidemiological Study of Periocular Dermatitis in a Specialised Hospital Department

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2011
Contact dermatitis is frequent skin pathology and eyelids are one of the more frequent locations of this pathology. The objective of the present work was to study the population distribution of periocular dermatitis, determine the allergens which most ...
Rafael Rojo-España   +4 more
doaj  

Static tire properties analysis and static parameters derivation to characterising tire model using experimental and numerical solutions [PDF]

open access: yes, 2016
Tire-ground interaction plays substantial role in determining vehicle kinetics and kinematics yet a clear understanding of such an interaction outputs is complex process.
Wei, Chongfeng, Yang, Xiaoguang
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

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