Results 1 to 10 of about 191,816 (321)

Flexible Patched Brain Transformer model for EEG decoding [PDF]

open access: yesScientific Reports
Decoding the human brain using non-invasive methods is a significant challenge. This study aims to enhance electroencephalography (EEG) decoding by developing of machine learning methods.
Timon Klein   +2 more
doaj   +2 more sources

Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes

open access: yeseLife, 2021
A long-standing mystery in vertebrate Hedgehog signaling is how Patched 1 (PTCH1), the receptor for Hedgehog ligands, inhibits the activity of Smoothened, the protein that transmits the signal across the membrane. We previously proposed (Kinnebrew et al.,
Maia Kinnebrew   +10 more
doaj   +1 more source

Inhibiting hedgehog signal by a patched-1 antibody [PDF]

open access: yesCell Discovery
Qinli Hu   +3 more
doaj   +2 more sources

Shear recovery of patched reinforced concrete beams with web reinforcements [PDF]

open access: yesArchives of Civil Engineering, 2022
Damage occurring on a reinforced concrete beam (e.g. spalling) can reduce beam’s capacity to withstand external loads. The damage becomes more critical if it is occurred in the shear span since it may lead to shear failure. Patching to the damage zone by
Stefanus Adi Kristiawan   +2 more
doaj   +1 more source

Spatiotemporal Expression of SHH/GLI Signaling in Human Fetal Bladder Development

open access: yesFrontiers in Pediatrics, 2021
Objectives: Sonic hedgehog (SHH) signaling is important in bladder development. Mice with defective hedgehog signaling develop bladder anomalies. Clinically, urinary tract malformations are reported in human fetuses and infants with mutations of SHH and ...
Haibao Zhang   +14 more
doaj   +1 more source

Control of the dynamics and homeostasis of the Drosophila Hedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases [PDF]

open access: yesOpen Biology, 2015
The conserved Hedgehog (HH) signals control animal development, adult stem cell maintenance and oncogenesis. In Drosophila, the HH co-receptor Patched (PTC) controls both HH gradient formation and signalling.
Amira Brigui   +5 more
doaj   +1 more source

A Patched-Like Protein PsPTL Is Not Essential for the Growth and Response to Various Stresses in Phytophthora sojae

open access: yesFrontiers in Microbiology, 2021
Patched (Ptc) and Patched-related (Ptr) proteins containing sterol-sensing domains (SSD) and Patched domains are highly conserved in eukaryotes for lipid transport and metabolism.
Zhaolin Xue   +6 more
doaj   +1 more source

The hedgehog receptor patched is involved in cholesterol transport. [PDF]

open access: yesPLoS ONE, 2011
Sonic hedgehog (Shh) signaling plays a crucial role in growth and patterning during embryonic development, and also in stem cell maintenance and tissue regeneration in adults. Aberrant Shh pathway activation is involved in the development of many tumors,
Michel Bidet   +10 more
doaj   +1 more source

The Optimization of Welding Spots’ Arrangement in A-Pillar Patchwork Blank Hot Stamping

open access: yesMetals, 2023
With increasingly severe environmental problems, energy saving and environmental protection have become two important issues to be solved in the automobile industry.
Wenfeng Li   +3 more
doaj   +1 more source

Increased security through open source [PDF]

open access: yes, 2007
In this paper we discuss the impact of open source on both the security and transparency of a software system. We focus on the more technical aspects of this issue, combining and extending arguments developed over the years. We stress that our discussion
Anderson R.   +3 more
core   +9 more sources

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