Results 91 to 100 of about 33,084 (302)
Patched as a new target for adrenocortical carcinoma treatment
, 2018 Nous avons récemment démontré que le récepteur du morphogène Hedgehog, Patched, qui est exprimé dans de nombreux cancers, est un transporteur de multiples drogues qui contribue à la résistance des cellules cancéreuses à la chimiothérapie.
Hasanovic, Anida
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Numerical estimation of stress intensity factors in patched cracked plates [PDF]
, 1987 The fatigue and fracture performance of a cracked plate can be substantially improved, by providing patches as reinforcements. The effectivenessof the patches is related to the reduction they cause in the stress intensity factor (SIF) of the crack.
Chandra, Ramesh, Guruprasad, K
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FEBS Open Bio, EarlyView.This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill +4 more
wiley +1 more source
Stem Cell Reports, 2014 In the adult brain, self-renewal is essential for the persistence of neural stem cells (NSCs) throughout life, but its regulation is still poorly understood. One NSC can give birth to two NSCs or one NSC and one transient progenitor. A correct balance is
Julien Ferent +6 more
doaj +1 more source
FEBS Open Bio, EarlyView.This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel +4 more
wiley +1 more source
Stem Cell Reports, 2015 Symmetric and asymmetric divisions are important for self-renewal and differentiation of stem cells during neurogenesis. Although cerebellar granule neurogenesis is controlled by sonic hedgehog (SHH) signaling, whether and how this process is mediated by
Rong Yang +5 more
doaj +1 more source
FEBS Open Bio, EarlyView.5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley +1 more source
Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception
eLife, 2014 Cell surface reception of Sonic hedgehog (Shh) must ensure that the graded morphogenic signal is interpreted accordingly in neighboring cells to specify tissue patterns during development.
Shen Yue +10 more
doaj +1 more source
Kepler's equation and its application to the patched conic approximation
, 2023 Kepler's equation and its application to the patched conic ...
Fabrizio Pinto
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