Results 101 to 110 of about 191,816 (321)

Requirement of Smurf-mediated endocytosis of Patched1 in sonic hedgehog signal reception

open access: yeseLife, 2014
Cell surface reception of Sonic hedgehog (Shh) must ensure that the graded morphogenic signal is interpreted accordingly in neighboring cells to specify tissue patterns during development.
Shen Yue   +10 more
doaj   +1 more source

Genetic Diversity and Expanded Phenotypes in Dystonia: Insights From Large‐Scale Exome Sequencing

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Dystonia is one of the most prevalent movement disorders, characterized by significant clinical and etiological heterogeneity. Despite considerable heritability (~25%), the etiology in most patients remains elusive. Moreover, understanding correlations between clinical manifestations and genetic variants has become increasingly ...
Mirja Thomsen   +47 more
wiley   +1 more source

Regulators of canonical extensions are torsion: the smooth divisor case [PDF]

open access: yes, 2007
In this paper, we prove a generalization of Reznikov's theorem which says that the Chern-Simons classes and in particular the Deligne Chern classes (in degrees $>1$) are torsion, of a flat bundle on a smooth complex projective variety.
Iyer, Jaya N., Simpson, Carlos T.
core   +4 more sources

Time‐Frequency Fingerprint Analysis in SEEG Source‐Space to Identify the Epileptogenic Zone

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT This case study highlights the application of seizure fingerprint analysis in the source‐space of stereo‐EEG (SEEG) data to accurately localize the epileptogenic zone (EZ) in patients with complex cortical malformations. A 25‐year‐old female with extensive bilateral perisylvian polymicrogyria (PMG) presented with intractable focal seizures ...
Yash Shashank Vakilna   +10 more
wiley   +1 more source

Morphological and hemodynamic patterns of carotid stenosis treated by endarterectomy with patch closure versus stenting: a duplex ultrasound study

open access: yesClinics, 2010
OBJECTIVES: A duplex ultrasound study was performed to investigate morphological and hemodynamic patterns of carotid stenoses treated by endarterectomy with patch closure versus stenting.
Marcia Maria Morales   +8 more
doaj   +1 more source

Glial Fibrillary Acidic Protein Astrocytopathy Based on a Two‐Center Chinese Cohort Study

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glial fibrillary acidic protein astrocytopathy (GFAP‐A) is a recently defined nosological form belonging to the class of autoimmune inflammatory disorders affecting the central nervous system (CNS). Here, we report the clinical and MRI characteristics, treatment, and prognosis of a GFAP‐A cohort from two centers in China.
Ti Wu   +13 more
wiley   +1 more source

Cracking behaviour and its effect on the deflection of patched-reinforced concrete beam under flexural loading

open access: yesMATEC Web of Conferences, 2017
Under the influence of aggressive environment, structural concrete could exhibit degradation in various forms. One of the symptoms of the degradation could be shown in the form of local delamination of concrete cover.
Kristiawan Stefanus   +3 more
doaj   +1 more source

A distinct boundary between the higher brain's susceptibility to ischemia and the lower brain's resistance.

open access: yesPLoS ONE, 2013
Higher brain regions are more susceptible to global ischemia than the brainstem, but is there a gradual increase in vulnerability in the caudal-rostral direction or is there a discrete boundary? We examined the interface between `higher` thalamus and the
C Devin Brisson   +2 more
doaj   +1 more source

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