Biomechanical evaluation of patch augmentation in a rotator cuff repair model using a porcine flexor digitorum profundus tendon: influence of knot tying and time-zero stability [PDF]
Clinics in Shoulder and ElbowBackground This study evaluates the biomechanical effects of acellular dermal matrix (ADM) patch augmentation in a rotator cuff repair model and determines the effect of medial knot tying on time-zero stability.
Sung-Min Rhee +7 more
doaj +2 more sources
Flexible Patched Brain Transformer model for EEG decoding [PDF]
Scientific ReportsDecoding the human brain using non-invasive methods is a significant challenge. This study aims to enhance electroencephalography (EEG) decoding by developing of machine learning methods.
Timon Klein +2 more
doaj +2 more sources
Patched 1 reduces the accessibility of cholesterol in the outer leaflet of membranes
eLife, 2021 A long-standing mystery in vertebrate Hedgehog signaling is how Patched 1 (PTCH1), the receptor for Hedgehog ligands, inhibits the activity of Smoothened, the protein that transmits the signal across the membrane. We previously proposed (Kinnebrew et al.,
Maia Kinnebrew +10 more
doaj +1 more source
Spatiotemporal Expression of SHH/GLI Signaling in Human Fetal Bladder Development
Frontiers in Pediatrics, 2021 Objectives: Sonic hedgehog (SHH) signaling is important in bladder development. Mice with defective hedgehog signaling develop bladder anomalies. Clinically, urinary tract malformations are reported in human fetuses and infants with mutations of SHH and ...
Haibao Zhang +14 more
doaj +1 more source
Shear recovery of patched reinforced concrete beams with web reinforcements [PDF]
Archives of Civil Engineering, 2022 Damage occurring on a reinforced concrete beam (e.g. spalling) can reduce beam’s capacity to withstand external loads. The damage becomes more critical if it is occurred in the shear span since it may lead to shear failure. Patching to the damage zone by
Stefanus Adi Kristiawan +2 more
doaj +1 more source
Control of the dynamics and homeostasis of the Drosophila Hedgehog receptor Patched by two C2-WW-HECT-E3 Ubiquitin ligases [PDF]
Open Biology, 2015 The conserved Hedgehog (HH) signals control animal development, adult stem cell maintenance and oncogenesis. In Drosophila, the HH co-receptor Patched (PTC) controls both HH gradient formation and signalling.
Amira Brigui +5 more
doaj +1 more source
Frontiers in Microbiology, 2021 Patched (Ptc) and Patched-related (Ptr) proteins containing sterol-sensing domains (SSD) and Patched domains are highly conserved in eukaryotes for lipid transport and metabolism.
Zhaolin Xue +6 more
doaj +1 more source
Anais Brasileiros de Dermatologia, 2013 Patch tests were introduced as a diagnostic tool in the late nineteenth century. Since then, they have improved considerably becoming what they are today. Patch tests are used in the diagnostic investigation of contact dermatitis worldwide. Batteries or series previously studied and standardized should be used in patch testing.
Lazzarini, Rosana +2 more
openaire +5 more sources
The hedgehog receptor patched is involved in cholesterol transport. [PDF]
PLoS ONE, 2011 Sonic hedgehog (Shh) signaling plays a crucial role in growth and patterning during embryonic development, and also in stem cell maintenance and tissue regeneration in adults. Aberrant Shh pathway activation is involved in the development of many tumors,
Michel Bidet +10 more
doaj +1 more source
Numerical Investigation of Fatigue Behavior of Non-patched and Patched Aluminum/Composite Plates
European Mechanical Science, 2021 In this study, the fatigue behavior of composite patched and non-patched Al 5083 aluminum plates was numerically investigated. Al 5083 Aluminum plates with semi-circular notched (2, 3 and 4 mm long cracked) and "V" notched (30°, 45° and 60° angled) were ...
Hamit Adin +2 more
doaj +1 more source