PLoS Biology, 2013 Hedgehog signaling plays conserved roles in controlling embryonic development; its dysregulation has been implicated in many human diseases including cancers.
Shoujun Huang +16 more
doaj +1 more source
Steppes, savannahs, forests and phytodiversity reservoirs during the Pleistocene in the Iberian Peninsula [PDF]
, 2010 A palaeobotanical analysis of the Pleistocene floras and vegetation in the Iberian Peninsula shows the existence of patched landscapes with Pinus woodlands, deciduous and mixed forests, parklands (savannah-like), shrublands, steppes and grasslands ...
Agustí +259 more
core +3 more sources
Three-Impulse Return Orbit Design and Characteristic Analysis for Manned Lunar Missions
IEEE Access, 2020 Return orbit design and characteristic analysis are very important issues in manned lunar missions. In this paper, a three-impulse return orbit scheme is studied.
Lin Lu, Haiyang Li
doaj +1 more source
Predictive Modeling of High Temperature Performance of SMA-13 Cold Patch Asphalt Mixture Based on Fractal Theory [PDF]
E3S Web of ConferencesIn order to study the relationship between the high temperature performance of cold-patched asphalt mixtures and gradation fractal, 13 groups of SMA-13 asphalt mixtures were designed, and high temperature rutting test was carried out to study the high ...
Sun Zhaohui, Guo Ke, Xie Jieru
doaj +1 more source
The Influence of Binary Interactions in Infrared passbands of populations [PDF]
, 2010 In our evolutionary population synthesis models, the samples of binaries are reproduced by the 'patched' Monte Carlo simulation and the stellar masses, integrated J, H, K, L, L2 and M magnitudes, mass-to-light ratios and broad colours involving infrared ...
Barmby +31 more
core +1 more source
Con-Patch: When a Patch Meets Its Context [PDF]
IEEE Transactions on Image Processing, 2016 Measuring the similarity between patches in images is a fundamental building block in various tasks. Naturally, the patch-size has a major impact on the matching quality, and on the consequent application performance. Under the assumption that our patch database is sufficiently sampled, using large patches (e.g. 21-by-21) should be preferred over small
Yaniv Romano, Michael Elad
openaire +3 more sources
A Comprehensive Study of Automatic Program Repair on the QuixBugs Benchmark [PDF]
, 2019 Automatic program repair papers tend to repeatedly use the same benchmarks. This poses a threat to the external validity of the findings of the program repair research community.
Durieux, Thomas +3 more
core +4 more sources
eLife, 2016 The Hedgehog signaling pathway is part of the ancient developmental-evolutionary animal toolkit. Frequently co-opted to pattern new structures, the pathway is conserved among eumetazoans yet flexible and pleiotropic in its effects. The Hedgehog receptor,
David S Lorberbaum +14 more
doaj +1 more source
Developmental Status: Impact of Short-Term Ischemia on Follicular Survival of Whole Ovarian Transplantation in a Rabbit Model. [PDF]
PLoS ONE, 2015 Ischemia is the first mechanism that provokes the loss of follicles in ovarian grafts over the long term. In whole ovarian transplantation, it remains unknown, however, how changes in follicular development are influenced by short-term ischemia.
Shuangshuang Xie +7 more
doaj +1 more source
Shortened primary cilium length and dysregulated Sonic hedgehog signaling in Niemann-Pick C1 disease [PDF]
, 2017 The Niemann-Pick type C1 (NPC1) disease is a neurodegenerative lysosomal storage disorder due to mutations in the NPC1 gene, encoding a transmembrane protein related to the Sonic hedgehog receptor, Patched, and involved in intracellular trafficking of ...
Canterini, Sonia +7 more
core +1 more source