Results 71 to 80 of about 199,906 (316)

Coming: a Tool for Mining Change Pattern Instances from Git Commits

open access: yes, 2018
Software repositories such as Git have become a relevant source of information for software engineer researcher. For instance, the detection of Commits that fulfill a given criterion (e.g., bugfixing commits) is one of the most frequent tasks done to ...
Martinez, Matias, Monperrus, Martin
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira   +14 more
wiley   +1 more source

Counterfeit Detection of Iranian Black Tea Using Image Processing and Deep Learning Based on Patched and Unpatched Images

open access: yesHorticulturae
Tea is central to the culture and economy of the Middle East countries, especially in Iran. At some levels of society, it has become one of the main food items consumed by households.
Mohammad Sadegh Besharati   +5 more
doaj   +1 more source

Quantum Hall Effect and Quantum Point Contact in Bilayer-Patched Epitaxial Graphene

open access: yes, 2014
We study an epitaxial graphene monolayer with bilayer inclusions via magnetotransport measurements and scanning gate microscopy at low temperatures. We find that bilayer inclusions can be metallic or insulating depending on the initial and gated carrier ...
Chua, C. J.   +12 more
core   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

Identification and Validation of Novel Hedgehog-Responsive Enhancers Predicted by Computational Analysis of Ci/Gli Binding Site Density.

open access: yesPLoS ONE, 2015
The Hedgehog (Hh) signaling pathway directs a multitude of cellular responses during embryogenesis and adult tissue homeostasis. Stimulation of the pathway results in activation of Hh target genes by the transcription factor Ci/Gli, which binds to ...
Katherine Gurdziel   +9 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

Classification of Sleep Apnea Severity by Electrocardiogram Monitoring Using a Novel Wearable Device

open access: yesSensors, 2020
Sleep apnea (SA) is a prevalent disorder diagnosed by polysomnography (PSG) based on the number of apnea−hypopnea events per hour of sleep (apnea−hypopnea index, AHI).
Florent Baty   +8 more
doaj   +1 more source

Reconstruction of the Aortic Arch in Neonates and Infants: The Importance of Patch Material [PDF]

open access: hybrid, 2021
Ingrid M. van Beynum   +6 more
openalex   +1 more source

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