Results 211 to 220 of about 1,660,326 (362)

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Investigation on current situation of Chinese patent medicines for children in China based on the national drug coding database. [PDF]

Front Pharmacol
Liu H, Rong P, Zhang Y, You Y, Fu Q, Cai L, Wei J, Ma R.   +7 more
europepmc   +1 more source

Arachnodactyly with Congenital Heart Disease (? Patent Interventricular Septum) [PDF]

, 1935
E. A. Cockayne
openalex   +1 more source

Navigating the Patent Thicket: Cross Licenses, Patent Pools, and Standard Setting

Innovation Policy and the Economy, 2000
C. Shapiro
semanticscholar   +1 more source

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

Molecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka, Tatsuo Nakagawa, Yusuke Ono, Yoshio Kamura, Takeshi Ishida, Hidemasa Kawabata, Kenji Takahashi, Hiroki Sato, Andrew S. Liss, Yusuke Mizukami, Takahide Yokoi   +10 more
wiley   +1 more source

Vivianite and Its Oxidation Products in Mammoth Ivory and Their Implications to the Burial Process

ACS Omega, 2021
Mengmeng Shen, Zhiyun Lu, Yan Xu, Xuemei He   +3 more
doaj   +1 more source

Global research trends on Chinese patent drugs inducing programmed cell death in cancer: a bibliometric analysis (1998-2024). [PDF]

Discov Oncol
Song M, Teng C, Zheng X, Tan S, Guo Y.
europepmc   +1 more source

THE BIOLOGICAL VALUE OF THE NITROGEN OF MIXTURES OF PATENT WHITE FLOUR AND ANIMAL FOODS

, 1926
H.H. Mitchell, G. G. Carman
openalex   +1 more source

A METHOD OF DETERMINING THE PATENCY OF THE FALLOPIAN TUBES BY X RAYS [PDF]

, 1925
Erik A. Williams, R. M. Reynolds
openalex   +1 more source

Comparing self‐reported race and genetic ancestry for identifying potential differentially methylated sites in endometrial cancer: insights from African ancestry proportions using machine learning models

Molecular Oncology, EarlyView.
Integrating ancestry, differential methylation analysis, and machine learning, we identified robust epigenetic signature genes (ESGs) and Core‐ESGs in Black and White women with endometrial cancer. Core‐ESGs (namely APOBEC1 and PLEKHG5) methylation levels were significantly associated with survival, with tumors from high African ancestry (THA) showing ...
Huma Asif, J. Julie Kim
wiley   +1 more source