Results 51 to 60 of about 1,320,431 (321)

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

open access: yesFEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

TERM EXTENSION OF DRUG PATENTS IN RUSSIA (REVIEW OF LEGISLATION AMENDMENTS)

open access: yesРазработка и регистрация лекарственных средств, 2019
The article describes the procedure of patent term extension to be granted on inventions relating to drugs and of granting a supplementary patent in view of recent amendments introduced in the Civil Code of the Russian Federation.
K. V. Osipov
doaj  

Patenting insurance related business methods: predictability and risk [PDF]

open access: yes, 2003
This paper raises and responds to questions concerning the patentability of business method patents. It explores the utility of patent applications in informing business method innovators of the risks associated with using the patent system.
Soetendorp, Ruth
core  

Interaction vesicles as emerging mediators of host‐pathogen molecular crosstalk and their implications for infection dynamics

open access: yesFEBS Letters, EarlyView.
Interaction extracellular vesicles (iEVs) are hybrid vesicles formed through host‐pathogen communication. They facilitate immune evasion, transfer pathogens' molecules, increase host cell uptake, and enhance virulence. This Perspective article illustrates the multifunctional roles of iEVs and highlights their emerging relevance in infection dynamics ...
Bruna Sabatke   +2 more
wiley   +1 more source

Estimation of genetic parameters and breeding values for litter size in the first three parity of Landrace sows [PDF]

open access: yesBiotechnology in Animal Husbandry, 2016
The aim of this study was to estimate the genetic parameters and breeding values for reproduction traits of Landrace sows in the first three parities by Animal model.
Lukač Dragomir   +3 more
doaj  

Who Cares About Patents? Cross-Industry Differences in the Marginal Value of Patent Term [PDF]

open access: yes, 2019
How much do market participants in different industries value a marginal change in patent term (i.e., duration of patent protection)? We explore this research question by measuring the behavioral response of patentees to a rare natural experiment: a ...
Cramer, Judd N.L., Sukhatme, Neel U.
core   +1 more source

A stepwise emergence of evolution in the RNA world

open access: yesFEBS Letters, EarlyView.
How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley   +1 more source

Patentgeographie

open access: yesRaumforschung und Raumordnung, 2001
The patents system provides a suitable instrument for monitoring and analysing developments both of a technological/scientific and of an economic nature.
Siegfried Greif
doaj   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy