Results 91 to 100 of about 794,896 (338)
The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity
FEBS Letters, EarlyView.The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley +1 more source
Research of the Patent Map of Harmonic Reducer
Jixie chuandong, 2017 By using IPC classification method and data collection,the patent information hiding in the technological field of the harmonic reducer is mined. The corresponding patent map is drawn,the issues related to research harmonic reducer technology in the ...
Chen Zhilan, Chen Wei
doaj
Do Stronger Patents Induce More Innovation? Evidence from the 1988 Japanese Patent Law Reforms [PDF]
Does an expansion of patent scope induce more innovative effort by firms? This article provides evidence on this question by examining firm responses to the Japanese patent reforms of 1988.
Lee Branstetter, Mariko Sakakibara
core
FEBS Letters, EarlyView.PARP‐1 is a key enzyme in the DNA damage response, and its inhibition induces cancer cell death via synthetic lethality. Au(I)‐based drugs, such as aurothioglucose and sodium aurothiomalate, block PARP‐1's DNA‐dependent activity by targeting its zinc finger domains.
Uliana Bashtanova, Melinda Jane Duer
wiley +1 more source
Patents as a Measure for Eco-Innovation [PDF]
This paper examines the usefulness of patent analysis for measuring eco-innovation. The overall conclusion is that patents are a useful means for measuring environmentally motivated innovations, such as pollution control technologies and green energy ...
Frans P. de VRIES (University of Stirling) +2 more
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Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Peptide‐based ligand antagonists block a Vibrio cholerae adhesin
FEBS Letters, EarlyView.The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang +9 more
wiley +1 more source
Advances in Transdermal Drug Delivery Systems: A Bibliometric and Patent Analysis. [PDF]
Pharmaceutics, 2023 Cammarano A +3 more
europepmc +1 more source
Against the one-way-street: Analyzing knowledge transfer from industry to science [PDF]
This study aims at analyzing the differences in the factors that influence the probability of knowledge transfer within industry and from industry to science in the biotechnology sector.
Fier, Heide, Pyka, Andreas
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