Results 81 to 90 of about 274,605 (313)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Patent Portfolio Races in Concentrated Markets for Technology [PDF]

open access: yes
Patent application numbers grow exponentially in many industries, a phenomenon that has been linked to high fragmentation of patent ownership. Contradicting these findings and theoretical arguments, we show that such fragmentation is not a precondition ...
Joachim Henkel, Florian Jell
core  

Research of the Patent Map of Harmonic Reducer

open access: yesJixie chuandong, 2017
By using IPC classification method and data collection,the patent information hiding in the technological field of the harmonic reducer is mined. The corresponding patent map is drawn,the issues related to research harmonic reducer technology in the ...
Chen Zhilan, Chen Wei
doaj  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Patent Examination Decisions and Strategic Trade Behavior [PDF]

open access: yes
This paper examines whether strategic trade behavior can explain the fact that the US, Japanese and European Patent Offices – the USPTO, the JPO and the EPO – often make different decisions about whether to grant (or reject) a given patent application.
Elizabeth Webster   +2 more
core  

Patent Data in Economic Analysis

open access: yes, 2017
The issues discussed in this chapter constitute a voice in a methodological discussion on the scope and manners of the utilisation of patent statistics in economic research. The discussion comprises the following issues: the gist of a patent monopoly, the evolution of opinions on the benefits and costs of a patent monopoly, and the possibilities and ...
openaire   +3 more sources

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Basic indicators of innovation activities from Puerto Ricans : a patent-based analysis

open access: yes, 2006
Patents reflect the current inventive and innovation development in modern technology. Since this kind of document have become more available through electronic databases, the studies and interest for use patent indicators with other research related ...
Suárez-Balseiro, Carlos   +2 more
core  

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

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