Results 91 to 100 of about 274,605 (313)

Advances in Transdermal Drug Delivery Systems: A Bibliometric and Patent Analysis. [PDF]

Pharmaceutics, 2023
Cammarano A, Dello Iacono S, Meglio C, Nicolais L.   +3 more
europepmc   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Patent analysis of digital sensors for continuous glucose monitoring. [PDF]

Front Public Health, 2023
Litvinova O, Eitenberger M, Bilir A, Yeung AWK, Parvanov ED, MohanaSundaram A, Horbańczuk JO, Atanasov AG, Willschke H.   +8 more
europepmc   +1 more source

Measuring technology catching up of automotive industry in Thailand by text mining of patent information [PDF]

Asia Pacific Journal of Innovation and Entrepreneurship
PurposeThis study endeavor aims to investigate the extent to which the Thai automotive industry has achieved technological parity with multinational firms operating within the nation.Design/methodology/approachThe methodology used in this study uses text
Suchit Pongnumkul, Kazuyuki Motohashi
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Patent Systems for Encouraging Innovation: Lessons from Economic Analysis [PDF]

Economic theory views patents as policy instruments aimed at fostering innovation and diffusion. Three major implications are drawn regarding current policy debates.
David Encaoua, Catalina Martínez, Dominique Guellec   +2 more
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Are All Patent Examiners Equal? The Impact of Examiner Characteristics [PDF]

Building on insights gained from interviewing administrators and patent examiners at the United States Patent and Trademark Office (USPTO), we collect and analyze a novel dataset on patent examiners and patent outcomes.
Scott Stern, Iain M. Cockburn, Samuel Kortum   +2 more
core  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

Monetizing Usage of Scholarly Collections with Patent Citation Analysis.

, 2006
Based on a series of independent studies conducted by Dr. Anthony Breitzman of 1790 Analytics, IEEE has learned that granted patents cite scientific and the technical literature found in journal articles, conference papers and industry standards.
Canning, Paul
core