Results 121 to 130 of about 274,605 (313)

Cost Benefit Analysis of the Community Patent

open access: yes
The creation of a European Community Patent (COMPAT) came a step closer this month when Sweden brokered a preliminary agreement on the issue. In this working paper, Senior Resident Fellow Bruno van Pottelsberghe and Jérôme Danguy use simulations to take ...
Bruno van Pottelsberghe, Jérôme Danguy
core  

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Regional innovation measured by patent data – does quality matter? [PDF]

open access: yes
Patent data play an important role as indicators of inventive and innovative activity across regions. This paper examines if the geographical distribution changes and in what direction if patent data are quality-adjusted.
Ejermo, Olof
core  

The market value of blocking patent citations. [PDF]

open access: yes
There is a growing literature that aims at assessing the private value of knowledge assets and patents. It has been shown that patents and their quality as measured by citations received by future patents contribute significantly to the market value of ...
Czarnitzki, Dirk   +2 more
core   +2 more sources

The Innovative Potential of Key Mentha Species: An Assessment Based on Patent Analysis

open access: yesBiology and Life Sciences Forum
Morocco’s rich biodiversity includes various aromatic and medicinal plants utilized for culinary and medicinal purposes. The genus Mentha, belonging to the Lamiaceae family, is notable for its widespread use in Moroccan culture.
Reda El Boukhari, Ahmed Fatimi
doaj   +1 more source

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

Patent Reform: Aligning Reward and Contribution [PDF]

open access: yes
Economists and policy makers have long recognized that innovators must be able to appropriate a reasonable portion of the social benefits of their innovations if innovation is to be suitably rewarded and encouraged.
Carl Shapiro
core  

The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes

open access: yesFEBS Letters, EarlyView.
Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga   +3 more
wiley   +1 more source

Knowledge spillover, licensing and patent protection [PDF]

open access: yes
This paper investigates the effect of different patent regimes on R&D investment and social welfare in a duopoly market with uncertain R&D process. We find that strong patent protection increases R&D investment of at least one firm but whether both ...
Mukherjee, Arijit
core  

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