Results 131 to 140 of about 274,605 (313)
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
A Welfare Analysis of Global Patent Protection in a Model with Endogenous Innovation and Foreign Direct Investment [PDF]
This paper constructs a North-South quality-ladder model in which foreign direct investment (FDI) is determined by the endogenous location choice of firms, and examines analytically how strengthening patent protection in the South affects welfare in the ...
Tatsuro Iwaisako +2 more
core
Environmental Research LettersAs the global energy sector transitions towards a cleaner and more sustainable future, observational evidence suggests that many new energy technologies share a close relationship with well-established technologies.
Yiwen Wang, Erin Baker, Anna Goldstein
doaj +1 more source
Exploring the nanobody patent landscape: a focus on BCMA sequences and structural analysis
mAbsNanobodies (Nbs) are antigen-binding fragments derived from unique heavy-chain-only antibodies. In recent years, the development of Nbs has progressed rapidly due to their therapeutic potential.
Jiaqi Xu +4 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
R&D, Licensing and Patent Protection [PDF]
This paper investigates the effect of different patent regimes on R&D investment and social welfare in a duopoly market with uncertain R&D process. We find that strong patent protection increases R&D investment of at least one firm but whether both firms’
Arijit Mukherjee
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
"Patent Activity and Technical Change" [PDF]
This paper presents an aggregate production function of the generalized Fechner-Thurstone (GFT) form to analyze the impact of an important component of intellectual industrial property, namely patent activity, on technical change in the USA for the ...
Michael McAleer +2 more
core
Patent Value Characterization -- An Empirical Analysis of Elevator Industry Patents
CoRRThe global patent application count has steadily increased, achieving eight consecutive years of growth.The global patent industry has shown a general trend of expansion. This is attributed to the increasing innovation activities, particularly in the fields of technology, healthcare, and biotechnology.
Yuhang Guan +3 more
openaire +2 more sources
FEBS Letters, EarlyView.Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure +3 more
wiley +1 more source