Results 131 to 140 of about 23,680,743 (297)
TO PATENT OR NOT TO PATENT: THE ROLE OF OPTIMAL PATENT BREADTH AND THE DECISION TO DEFEND THE PATENT RIGHT [PDF]
The paper examines the relationship between the innovator's patenting and patent breadth decisions as well as how these two decisions affect, and are affected by, the innovator's ability to enforce her patent rights.
Yiannaka, Amalia, Fulton, Murray E.
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Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Analysis of World Experience and Experimental Implementation of Unmanned Radio Intelligence Systems
Transport and TelecommunicationThe article presents a comprehensive review and experimental analysis of the development of unmanned systems designed for electronic reconnaissance (REI) tasks.
Yermoldina Gulnaz +3 more
doaj +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
A Patent Landscape Analysis of Textile Sensors for Muscular Activity Sensing of Stimulation
Engineering ProceedingsIn the era of smart garments, textile electrodes for electromyography (EMG) or functional electric stimulation (FES) represent a very interesting and promising area of development and exploitation.
Massimo Barbieri, Giuseppe Andreoni
doaj +1 more source
Analysis of antiretroviral drugs patenting and patent laws facilitating their access
Medicine of Ukraine, 2015 The purpose of this study is to analyze the patent protection of antiretrovi-ral drugs in Ukraine and abroad, as well as the legal norms of foreign regula-tory authorities, facilitating their access for patients with HIV. It was found that the introduction of international standards in the field of intellectual property rights protection in Ukraine has
openaire +3 more sources
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
EnergiesAgainst the background of carbon neutrality and the global energy transition, biomass-derived nanocellulose has attracted increasing attention because of its renewability, biodegradability, low density, high mechanical strength, and tunable surface ...
Qimei Chen +6 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Cost Benefit Analysis of the Community Patent [PDF]
The creation of a European Community Patent (COMPAT) came a step closer this month when Sweden brokered a preliminary agreement on the issue. In this working paper, Senior Resident Fellow Bruno van Pottelsberghe and Jérôme Danguy use simulations to take ...
Bruno van Pottelsberghe, Jérôme Danguy
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