Results 181 to 190 of about 794,896 (338)

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Development of the patent array analysis module based on the “Problem-Solution” model

, 2021
O A Kochura, Dmitriy Korobkin, Sergey Fomenkov, Sergey Kolesnikov   +3 more
openalex   +1 more source

Post-Issue Patent "Quality Control": A Comparative Study of US Patent Re-examinations and European Patent Oppositions [PDF]

We report the results of the first comparative study of the determinants and effects of patent oppositions in Europe and of re-examinations on corresponding patents issued in the United States. The analysis is based on a dataset consisting of matched EPO
Bronwyn H. Hall, David C. Mowery, Dietmar Harhoff, Stuart J. H. Graham   +3 more
core  

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Patent Analysis

International Journal for Research in Applied Science and Engineering Technology, 2019
openaire   +1 more source

Hydrogen station technology development review through patent analysis [PDF]

, 2018
Chengyu Wen, Guangli He
openalex   +1 more source

Patent Foramen Ovale Closure for Treating Migraine: A Meta-Analysis [PDF]

, 2022
Yu Zhang, Haijiao Wang, Ling Liu
openalex   +1 more source

EFFECTS OF FOREIGN INTELLECTUAL PROPERTY RIGHTS ON U.S. BILATERAL EXPORTS OF BIOTECHNOLOGY RELATED AGRICULTURAL INPUTS [PDF]

This paper examines the effect of foreign intellectual property right (IPR) systems and the policies that comprise them on U.S. exports of biotechnology related agricultural input industries. Policy components include the extent of patent coverage across
Wisniewski, Suzanne L.W.
core   +1 more source

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

Molecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He, Chiara Testini, Neda Hekmati, Altea Bonello, Aglaia Schiza, Emmanuel Nwadozi, Mia Phillipson, Carina Strell, Michael Welsh   +8 more
wiley   +1 more source