Results 121 to 130 of about 19,095 (287)

TB vaccine development: monitoring international patent filings to anticipate access challenges

open access: yesFrontiers in Public Health
IntroductionEvery year, an estimated 10 million new cases of tuberculosis (TB) are diagnosed, and 1.6 million deaths occur worldwide due to this disease.
María Florencia Pignataro   +6 more
doaj   +1 more source

The worldwide patent landscape of dental implant technology. [PDF]

open access: yesBiomater Res, 2022
Kim WJ, Cho YD, Ku Y, Ryoo HM.
europepmc   +1 more source

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

open access: yesMolecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach   +9 more
wiley   +1 more source

Patent Landscape Report on Solar Cooling Technologies Dataset. [PDF]

open access: yes
This patent landscape report provides a general overview of existing solar cooling technologies and potential fields of application. It includes applications that go beyond air-conditioning, such as the cooling of water; refrigeration of sensitive goods,

core   +1 more source

Innovating Patent Retrieval: A Comprehensive Review of Techniques, Trends, and Challenges in Prior Art Searches

open access: yesApplied System Innovation
As the patent landscape continues to grow, so does the complexity of retrieving relevant “prior art”, “background art”, or “state of the art” from an expanding pool of publicly available patent data, a critical step in establishing novelty.
Amna Ali   +3 more
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

Single‐cell DNA methylation profiling: Technologies, computation, and applications in precision oncology

open access: yesMolecular Oncology, EarlyView.
Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

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