Results 111 to 120 of about 1,552,229 (290)

United States Patent Office Grants, Disk USP031

, 2013
This dataset contains the compiled Optical Character Recognition (OCR) text files for the content of patent grants issued by the United States Patent Office from ## to ## (non-inclusive)
Phillips, Mark Edward
core  

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

TB vaccine development: monitoring international patent filings to anticipate access challenges

Frontiers in Public Health
IntroductionEvery year, an estimated 10 million new cases of tuberculosis (TB) are diagnosed, and 1.6 million deaths occur worldwide due to this disease.
María Florencia Pignataro, María Florencia Pignataro, Carolinne Thays Scopel, María Lorena Bacigalupo, Mike Frick, Sergiy Kondratyuk, Gabriela Costa Chaves   +6 more
doaj   +1 more source

The worldwide patent landscape of dental implant technology. [PDF]

Biomater Res, 2022
Kim WJ, Cho YD, Ku Y, Ryoo HM.
europepmc   +1 more source

Patent trolls and patent-busters

, 2008
In recent times, there have been concerns that the patent system been abused by opportunistic companies known by the phrase "patent trolls". It has been alleged that such entities have stunted innovation and spurred unnecessary patent litigation..
Rimmer, Matthew
core  

Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA

FEBS Open Bio, EarlyView.
PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro, Fernando Lucas Palhano   +1 more
wiley   +1 more source

Innovating Patent Retrieval: A Comprehensive Review of Techniques, Trends, and Challenges in Prior Art Searches

Applied System Innovation
As the patent landscape continues to grow, so does the complexity of retrieving relevant “prior art”, “background art”, or “state of the art” from an expanding pool of publicly available patent data, a critical step in establishing novelty.
Amna Ali, Ali Tufail, Liyanage Chandratilak De Silva, Pg Emeroylariffion Abas   +3 more
doaj   +1 more source

Dredge.

, 1921
Patent for an excavating machine specifically designed for canal digging, that "is an improvement upon a patent granted to Charles S. Butterfield, March 13, 197 and numbered 1,219,371" (lines 10-13).
Evans, Marvin
core  

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

FEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya, Masatake Osawa, Hidefumi Fukumitsu   +2 more
wiley   +1 more source

An Overview of the Additive Manufacturing of Bast Fiber-Reinforced Composites and Envisaging Advancements Using the Patent Landscape. [PDF]

Polymers (Basel), 2023
Balaji D, Arulmurugan B, Bhuvaneswari V.
europepmc   +1 more source