Results 101 to 110 of about 19,095 (287)

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

open access: yesMolecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary   +1 more
wiley   +1 more source

Navigating through the patent landscape: The legal implications for a biotechnology SME in New Zealand [PDF]

open access: yes, 2012
Full Text is available to authenticated members of The University of Auckland only.The proliferation of patents in the biotechnology research space has raised concerns among scholars regarding the possible stifling effect of overlapping patents (patent ...
Wadasinghe, Maheshi
core  

Phage therapy for environmental biotechnology applications

open access: yesFrontiers in Microbiology
Environmental compartments, from soils and crop rhizospheres, to bio-reactors and municipal water networks have emerged as dynamic hot-spots for antimicrobial-resistance evolution and dissemination.
Suniti Singh   +3 more
doaj   +1 more source

Flow Enabled Target Capture Halbach‐based magnetic enrichment increases circulating tumor cell capture from blood in metastatic cancer patients

open access: yesMolecular Oncology, EarlyView.
Pair‐wise comparison of the CellSearch and FETCH enrichment technologies for circulating tumor cells (CTCs) from metastatic breast, prostate, and small cell lung cancer patients shows an increased capture of CTCs using FETCH enrichment. The clinical implementation of circulating tumor cells (CTCs) as a predictive tool for therapy efficacy in the ...
Michiel Stevens   +6 more
wiley   +1 more source

A Patent Landscape Analysis of Textile Sensors for Muscular Activity Sensing of Stimulation

open access: yesEngineering Proceedings
In the era of smart garments, textile electrodes for electromyography (EMG) or functional electric stimulation (FES) represent a very interesting and promising area of development and exploitation.
Massimo Barbieri, Giuseppe Andreoni
doaj   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

The unified patent court as part of a new European patent landscape : wholesale harmonization or experiment in legal pluralism? [PDF]

open access: yes, 2018
The European field of intellectual property law is on the brink of exciting changes as the Unified Patent Court (UPC) and the European Patent with unitary effect may soon see the light of day. This will have significant consequences for the protection of
VAN PADDENBURGH, Cato   +1 more
core  

Innovation trends in industrial biotechnology: a patent landscape analysis [PDF]

open access: yes
This report presents a patent landscape analysis investigating the innovation trends within the industrial biotechnology (IB) sector from 2015 to 2020. The study's primary objective is to identify the geographical hotspots of innovation, the key players,
PELISSIER Pierre-Mathieu   +2 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Developments in Leishmaniasis diagnosis: A patent landscape from 2010 to 2022. [PDF]

open access: yesPLOS Glob Public Health, 2023
de Avelar DM   +2 more
europepmc   +1 more source

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