Results 71 to 80 of about 19,095 (287)
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
China’s Robotics Patent Landscape [PDF]
, 2021 Since 2011, China has dramatically grown its robotics sector as part of its mission to achieve technological leadership. The Chinese government has encouraged this growth through incentives and, in some cases, subsidies. Patents in robotics have surged, particularly at Chinese universities; by contrast, private companies comprise the bulk of robotics ...
openaire +1 more source
FEBS Letters, EarlyView.Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
From mice to humans—divergent strategies for intestinal homeostasis and regeneration
FEBS Letters, EarlyView.Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa +2 more
wiley +1 more source
Landscape Analysis of Patent Dataset [PDF]
, 2016 211-225With the advancement of technology in almost all sectors of industry and decreasing span of product, inventing new ideas are required for any industry.
Nagpal, Renuka +3 more
core
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Patent landscape of Aquilaria species: trends in sustainable agarwood agribusiness innovation [PDF]
Aquilaria spp. is renowned for its fragrant, resin-impregnated wood, commonly known as agarwood, which is highly valued in the perfumery industry. Beyond this prized resin, the tree yields a wide range of materials – including leaves, fruits, seeds ...
Mohd Rozali, Nur Erina Syafiqa +7 more
core
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Lost property: The European patent system and why it doesn't work [PDF]
In his blueprint, Bruno van Pottelsberghe first looks at the performance of patent arrangements in Europe, especially their cost effectiveness and the consistency of rules and remedies across countries.
Bruno van Pottelsberghe
core +1 more source