Results 71 to 80 of about 1,387,926 (283)
The reflection of the struggle of Russian companies for promising markets in the patent statistics
Ekonomika Nauki, 2017 The article analyzes data from the annual report of the European patent agency, reflecting the struggle of industrialized countries for the EU market in the projection of the patent landscape of 2016.
N. G. Kurakova
doaj +1 more source
Molecular Oncology, EarlyView.Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson +9 more
wiley +1 more source
Wave and Tidal Energy: A Patent Landscape Study
Journal of Marine Science and EngineeringWave and tidal energy, recognized as vital renewable resources, harness the ocean’s kinetic and potential power. This study aims to provide an in-depth patent analysis of the technological landscape within these sectors. We applied a dual approach: first,
Mohamadreza Pazhouhan +4 more
semanticscholar +1 more source
Molecular Oncology, EarlyView.Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
CoatingsThis study addresses the gap in research on the application of thermochromic polymers (TPs) in food packaging and their potential for real-time temperature monitoring, aiding in the assessment of food quality and shelf-life.
C. Breheny +5 more
semanticscholar +1 more source
Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer
Molecular Oncology, EarlyView.COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann +61 more
wiley +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source
China’s Robotics Patent Landscape [PDF]
, 2021 Since 2011, China has dramatically grown its robotics sector as part of its mission to achieve technological leadership. The Chinese government has encouraged this growth through incentives and, in some cases, subsidies. Patents in robotics have surged, particularly at Chinese universities; by contrast, private companies comprise the bulk of robotics ...
openaire +1 more source
Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma
Molecular Oncology, EarlyView.The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic +5 more
wiley +1 more source