Results 121 to 130 of about 2,744,703 (304)
Patent reform: a mixed blessing for the U.S. economy? [PDF]
The 1980s represented a period of dramatic change in the design and enforcement of U.S. intellectual property law. Many of these changes were adopted in the hopes of stimulating private research and development and improving the technological ...
Robert Hunt
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Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Public Disclosure of Patent Applications, R & D, and Welfare [PDF]
In this paper we examine the consequences of this difference for (i) firm's R&D and patenting behavior, (ii) consumers' surplus and social welfare, and (iii) the incentives of firms to innovate, in a setting where patent protection is imperfect in the ...
Reiko Aoki, Yossef Spiegel
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Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer
Molecular Oncology, EarlyView.Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba +5 more
wiley +1 more source
Do Stronger Intellectual Property Rights Protection Induce More Bilateral Trade? Evidence from China's Imports [PDF]
Most of the previous studies on the effect of IPR protection on international trade have been from the perspective of major industrialized nations. However, much of the current debate on the effects of IPR protection involves large developing countries ...
Yin, Hong, Awokuse, Titus O.
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Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
Global laws governing intellectual property rights for AI-generated works
Discover Artificial IntelligenceArtificial intelligence (AI) generates works in fields such as literature, arts, and inventions. This development has driven growth in patent applications involving AI-generated inventions and intensified legal uncertainty over the scope of copyright ...
Tiyyaba Furqan +3 more
doaj +1 more source
Patent protection for CRISPR: an ELSI review. [PDF]
J Law Biosci, 2017 Sherkow JS.
europepmc +1 more source
Patent protection of biotechnological inventions and the limits of patentability [PDF]
, 2015 <span>Biotechnology, which concerns living matter, poses significant challenges for patent law, given that biotechnological inventions do not fall so neatly under the classical model, as do those of mechanics. On the other hand, the reasons at the foundation of patent protection, which in particular are the incentive to innovation and disclosure ...
openaire +1 more source
Strenghtening Intellectual Property rights: Experience from the 1986 Taiwanese Patent Reforms [PDF]
Intellectual property rights (IPR) have recently moved to the forefront of debates over international policy. As each country establishes its own institutions of IPR, a divergence exists between net producers and net consumers in the returns to providing
Shih-Tse Lo
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