Results 41 to 50 of about 4,974 (149)

Utilização e custo de medicamentos em gestantes de baixo-risco [PDF]

open access: yes, 2008
The objective of the present study is to assess the use of medication by pregnant women; classify them regarding therapy group and its risk category; and identify the cost of these drugs.
MAEDA, Sayuri Tanaka   +1 more
core   +4 more sources

Impact of C18 Epimerization of Indole‐ and Pyrazole‐Fused 18β‐Glycyrrhetinic Acid Derivatives on PTP1B and TCPTP Inhibitory Activity: Synthesis, In Vitro, and In Silico Studies

open access: yesChemMedChem, Volume 20, Issue 22, November 18, 2025.
The indole derivative (FC‐114) and the N‐phenylpyrazole (FC‐122) of glycyrrhetinic acid are both potent inhibitors of the Protein Tyrosine Phosphatase 1B, with IC50 values of 0.48 μM and 1.15 μM, respectively. However, their activity decreases by up to four times when the 18β‐H position is epimerized to 18α‐H or when the carbonyl group at the C11 ...
Ledy De‐la‐Cruz‐Martínez   +10 more
wiley   +1 more source

La mercantilización del derecho a la salud: patentes farmacéuticas

open access: yesDeusto Journal of Human Rights, 2017
In spite of the great developments in medicine in the 20th century, the healthcare and the quality of life of millions of people living in developing countries are still under the acceptable limits.
Lourdes Collado Rodríguez
doaj   +1 more source

Comércio internacional, patentes e saúde pública [PDF]

open access: yes, 2006
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Jurídicas. Programa de Pós-graduação em DireitoO tema geral desta dissertação é a análise da complexa relação entre o comércio internacional, patentes e saúde pública. Em
Guise, Mônica Steffen
core  

Study of brain perfusion in adults with Down syndrome along the Alzheimer's disease continuum

open access: yesAlzheimer's &Dementia, Volume 21, Issue 9, September 2025.
Abstract INTRODUCTION We assessed pseudo‐continuous arterial spin labeling (pCASL) sensitivity to detect changes in cerebral blood flow (CBF) in adults with Down syndrome (DS) along the Alzheimer's disease (AD) continuum and explored the similarity with sporadic AD (sAD) hypoperfusion profile.
Maria Franquesa‐Mullerat   +21 more
wiley   +1 more source

Estratégia de proteção de patentes farmacêuticas: o caso do atazanavir

open access: yesRECIIS, 2016
O alto custo dos medicamentos antirretrovirais (ARVs) justifica estudos sobre estratégias de patenteamento farmacêutico vis-à-vis à política pública brasileira de acesso universal aos ARVs.
Carla Cristina de Freitas da Silveira   +2 more
doaj   +1 more source

Reflections on human embryo research: the debate in Portuguese ethics organizations [PDF]

open access: yes, 2013
Analisam-se os argumentos usados pelas organizações de ética portuguesas na regulação da investigação em embriões de origem humana. Recolheram-se documentos produzidos entre 2006 e 2010.
Alves, Bruno Rodrigues   +2 more
core   +3 more sources

Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of Faecalibacterium prausnitzii in Overweight Adults–A Double‐Blind Trial

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 17, September 2025.
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina   +15 more
wiley   +1 more source

Propiedad intelectual y patentes sobre usos medicinales en conocimientos tradicionales

open access: yesInvestigación Agraria, 2018
En este trabajo se analiza el conocimiento tradicional sobre las supuestas propiedades medicinales de plantas y sus usos, como parte de los bienes comunes, que tiene la protección del derecho interno y del derecho internacional. Se consideran los usos de
Ramón Fogel
doaj   +1 more source

TRANSFERÊNCIA DE CONHECIMENTO TECNOLÓGICO DA UNIVERSIDADE PARA O SETOR PRODUTIVO EM PORTUGAL [PDF]

open access: yes, 2010
A transferência de conhecimento (TC) é uma forma de melhorar a capacidade tecnológica das organizações, possibilitando orientar suas atividades para a inovação e a competitividade.
OTERO, WALTER RUBEN IRIONDO
core  

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