Results 31 to 40 of about 176 (123)

A Comprehensive Evaluation of Patient Satisfaction and Clinical Outcomes in Poly‐L‐Lactic Acid Treatments—A Randomized, Interventional, and Comparative Clinical Study

Journal of Cosmetic Dermatology, Volume 25, Issue 5, May 2026.
ABSTRACT Background Poly‐L‐lactic acid (PLLA) is widely used in aesthetic medicine due to its bio‐stimulatory properties. However, limited research has compared different PLLA formulations. Aim To evaluate the impact of PLLA formulation and injection depth (subcutaneous vs. supraperiosteal) using objective and subjective assessments.
Victor R. M. Munoz‐Lora, Danielle Dias, Fernanda Bezerra, Ana C. N. Carnevali, Rud Varela, Andrea D. Tedesco, Pietra Roschel, Gabriela Giro, Patrícia Pauletto, Victor Rogerio, Marcelo Germani   +10 more
wiley   +1 more source

Temporal dynamics of white matter hyperintensities related to Alzheimer's disease in adults with Down syndrome

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION White matter hyperintensities (WMH) are common in Down syndrome (DS), yet their longitudinal evolution and associations with Alzheimer's disease (AD) remain unclear. METHODS Longitudinal MRI study, including 80 DS adults and 53 euploid controls. WMH were segmented on serial FLAIR using a longitudinal pipeline.
Alejandra O. Morcillo‐Nieto, Mateus Rozalem‐Aranha, Lucia Maure‐Blesa, Íñigo Rodríguez‐Baz, José Enrique Arriola‐Infante, Maria Franquesa‐Mullerat, Sara E. Zsadanyi, Lídia Vaqué‐Alcázar, José Allende Parra, Zili Zhao, Javier Arranz, Laura Videla, Isabel Barroeta, Laura Del Hoyo Soriano, Bessy Benejam, Susana Fernández, Aida Sanjuan Hernandez, Lucia Pertierra, Sandra Giménez, Daniel Alcolea, Olivia Belbin, Alberto Lleó, María Carmona‐Iragui, Juan Fortea, Alexandre Bejanin   +24 more
wiley   +1 more source

Estratégia de proteção de patentes farmacêuticas: o caso do atazanavir

RECIIS, 2016
O alto custo dos medicamentos antirretrovirais (ARVs) justifica estudos sobre estratégias de patenteamento farmacêutico vis-à-vis à política pública brasileira de acesso universal aos ARVs.
Carla Cristina de Freitas da Silveira, Marilena Cordeiro Dias Villela Corrêa, Wanise Borges Gouvea Barroso   +2 more
doaj   +1 more source

Propiedad intelectual y patentes sobre usos medicinales en conocimientos tradicionales

Investigación Agraria, 2018
En este trabajo se analiza el conocimiento tradicional sobre las supuestas propiedades medicinales de plantas y sus usos, como parte de los bienes comunes, que tiene la protección del derecho interno y del derecho internacional. Se consideran los usos de
Ramón Fogel
doaj   +1 more source

Combined Neuroprotective Effects of N,N‐Dimethyltryptamine and Ventral Root Reimplantation Following Spinal Root Avulsion in Rats

Journal of Neurochemistry, Volume 170, Issue 2, February 2026.
The ventral root avulsion (VRA) model provides an excellent experimental paradigm for studying injuries at the Central/Peripheral Nervous Systems (CNS/PNS) interface. By physically disconnecting motoneurons (MNs) from the spinal cord surface, VRA induces profound cellular, molecular, and functional deficits with limited spontaneous recovery.
Paola Andrea Caro Aponte, Edison Huertas Montoya, Italo O. Mazali, Alessandra Sussulini, Benedito Barraviera, Rui Seabra Ferreira Jr., Luciana Politti Cartarozzi, Alexandre Leite Rodrigues de Oliveira   +7 more
wiley   +1 more source

Reflexiones sobre las nuevas directivas de patentabilidad para invenciones farmacéuticas

Revista Iberoamericana de la Propiedad Intelectual, 2013
Lo que se pretende es realizar un ejercicio de reflexión sobre la aplicación del sistema de patentes al ámbito de los medicamentos farmacéuticos tomando como tópico disparador la Resolución Conjunta citada.
Pablo Tomás Lamas
doaj  

From Lab to Industry: Advancing the Translational Potential of Extracellular Vesicles Through the ISEV Translation, Regulation and Advocacy Committee (ISEV‐TRA)

Journal of Extracellular Vesicles, Volume 15, Issue 1, January 2026.
ABSTRACT Extracellular vesicles (EVs) have emerged as powerful mediators of intercellular communication with significant potential across biomedical, veterinary, cosmetic, agricultural and environmental applications. However, the translation of EV‐based discoveries into practical and commercially viable products remains constrained by scientific ...
Uxia Gurriaran‐Rodriguez, Benedetta Bussolati, Mario Gimona, Konstantin Glebov, Yu Fujita, Antonio Marcilla, Christian Neri, Qing‐Ling Fu, Saumya Das, Stefano Pluchino, Natasa Zarovni, Carlos Salomon, Kenneth Witwer, Juan Manuel Falcon‐Perez   +13 more
wiley   +1 more source

An Integrated Engineering Approach to Creating Health‐Modulating Postbiotics

Molecular Nutrition &Food Research, Volume 70, Issue 1, January 2026.
Postbiotics have emerged as a promising alternative to live probiotics, offering comparable health benefits while overcoming challenges related to safety, stability, and shelf life. The review addresses current challenges in standardizing postbiotic definitions and production processes, and by outlining future research directions necessary to unlock ...
Michael Leonidas Chikindas, Diana E. Roopchand, Santosh Kumar Tiwari, Liubov S. Sichel, Mukund V. Karwe, Nitin Nitin, Vitor Luis Fagundes, Igor V. Popov, John R. Tagg, Xuanxuan Lu, Svetoslav Dimitrov Todorov   +10 more
wiley   +1 more source

Propriedade intelectual e saúde pública: a cópia de medicamentos contra HIV/Aids realizada por laboratórios farmacêuticos brasileiros públicos e privados

RECIIS, 2007
A experiência dos laboratórios brasileiros públicos e privados em copiar ARVs (anti-retrovirais), desde 1993, constitui um processo de aprendizado tecnológico que, em alguns casos, produziu inovações.
Maurice Cassier, Marilena Correa
doaj   +1 more source

Yerba Mate (Ilex paraguariensis A. St.‐Hil.) Reduces Oxidative Stress and Bone Resorption in Apical Periodontitis

International Endodontic Journal, Volume 59, Issue 1, Page 91-104, January 2026.
ABSTRACT Aim Apical periodontitis (AP) is a highly prevalent chronic inflammatory disease that can exert systemic effects by releasing biochemical mediators that initiate and regulate the immune response. Yerba Mate (Ilex paraguariensis, YM), a popular plant broadly consumed in South America, is rich in biologically active compounds known for their ...
Carolina Sayuri Wajima, Carolina de Barros Morais Cardoso, Caroline Anselmi, Renan Dal‐Fabbro, Murilo Catelani Ferraz, Cristiane Cantiga da Silva, Paulo César Ciarlini, Edilson Ervolino, Marco Cícero Bottino, Luciano Tavares Angelo Cintra   +9 more
wiley   +1 more source