Results 31 to 40 of about 59,453 (156)

Sharing the Burden: The Impacts of Pharmacy Sector Reforms on the Labor Market for Pharmacists in Portugal

Industrial Relations: A Journal of Economy and Society, EarlyView.
ABSTRACT During the 2010 crisis, the Portuguese government enacted several reforms to its prescription drug reimbursement system. As a result, value added per pharmacist in pharmacies fell by a third. We use longitudinal records from Quadros de Pessoal (QP), merged with collective bargaining data and firm financial records, to study the impacts of the ...
David Card, Ana Rute Cardoso, Pedro Luis Silva   +2 more
wiley   +1 more source

Os tratados de livre comércio e o acordo TRIPS: uma análise de proteção patentária na área farmacêutica [PDF]

, 2009
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Jurídicas. Programa de Pós-graduação em DireitoA adesão ao Acordo sobre Aspectos dos Direitos de Propriedade Intelectual relacionados ao Comércio (Acordo TRIPS) em 1994 ...
Silva, Francisco Viegas Neves da
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Patentes farmacéuticas en Brasil y T-MEC. Aproximaciones de dos regulaciones

Boletín Mexicano de Derecho Comparado
Las patentes son un privilegio temporal previstas en las legislaciones internacionales, acuerdos de libre comercio y en el derecho interno. Derivadas de las invenciones, necesitan cumplir requisitos fundamentales para solicitarse.
Marta Carolina Giménez Pereira, Salete Oro Boff, Vilmar Antônio Boff   +2 more
doaj   +1 more source

Changes in serum β‐synuclein precede blood biomarkers of Alzheimer pathology in Down syndrome

Alzheimer's &Dementia, Volume 22, Issue 9, September 2026.
Abstract INTRODUCTION There is a need for early, objective markers of Alzheimer's disease (AD)‐related synapse dysfunction in adults with Down syndrome (DS). The presynaptic protein β‐synuclein is elevated in the blood of adults with DS. This study evaluates the positioning of these changes relative to changes in pathophysiological blood biomarkers ...
Alba Cervantes González, Alejandra O Morcillo‐Nieto, Sara Serrano, Bessy Benejam, Laura Videla, Isabel Barroeta, Susana Fernández, Laura del Hoyo Soriano, Aida S Hernandez, Lucía Maure‐Blesa, Lídia Vaqué‐Alcázar, Javier Arranz, Íñigo Rodríguez‐Baz, Mateus R Aranha, Danna Perlaza, Laia Lidón, Daniel Alcolea, Alexandre Bejanin, María Carmona‐Iragui, Juan Fortea, Alberto Lleó, Markus Otto, Patrick Oeckl, Olivia Belbin   +23 more
wiley   +1 more source

Methamphetamine Enantiomers: From Chemical Synthesis to Biological Fate

Chirality, Volume 38, Issue 9, September 2026.
Methamphetamine is an amphetamine‐type stimulant characterized by a single stereogenic center, resulting in two enantiomers, (R)‐(−)‐methamphetamine and (S)‐(+)‐methamphetamine, with distinct biological and pharmacological profiles. These forms exhibit differences in central nervous system activity, metabolism, excretion, and overall physiological ...
Larissa Pires do Espírito Santo, Renato Lúcio de Carvalho, Juliana Almeida Sad, Pedro Henrique Costa dos Santos, Rhaiza Silva Domingues, Gabriele de Azevedo Cardoso, Karine Braga Enes, Gisele Assis Castro Goulart, Maila de Castro Lourenço das Neves, Ângelo de Fátima   +9 more
wiley   +1 more source

CSF fibrinogen predicts longitudinal Tau accumulation in cognitively unimpaired older adults

Alzheimer's &Dementia, Volume 22, Issue 8, August 2026.
Abstract INTRODUCTION Blood–brain barrier (BBB) dysfunction is an early feature of Alzheimer's disease (AD). Fibrinogen represents a sensitive marker of BBB leakage, but whether it modifies longitudinal tau progression in cognitively unimpaired (CU) individuals remains unknown.
Christos Panagiotis Lisgaras, Tovia Jacobs, Luisa Figueredo, Elizabeth Pirraglia, Caleb H Radtke, Jonah N Keller, Nikolaos Karvelas, Jennifer Bernal, Joaquin Ruiz, Henrik Zetterberg, Lidia Glodzik, Mony J de Leon, Laura Beth McIntire, Allal Boutajangout, Thomas Wisniewski, Jaime Ramos‐Cejudo, Daniel Alcolea, Sandra Giménez, Juan Fortea, Katerina Akassoglou, Fanny M Elahi, Ricardo S Osorio   +21 more
wiley   +1 more source

Criteria for Control and Remission of Respiratory Allergic Disease With Allergen Immunotherapy: A Delphi Consensus

Clinical and Translational Allergy, Volume 16, Issue 8, August 2026.
Expert consensus using a Delphi methodology proposed definitions of control and remission for allergic rhinitis, conjunctivitis and asthma in the context of allergen immunotherapy. These consensus‐based criteria integrate symptoms, medication use, patient‐reported outcomes and objective measures to support a more structured assessment of treatment ...
Eloína González‐Mancebo, Juan María Beitia Mazuecos, Ana I Tabar Purroy, Mar Gandolfo‐Cano, Adriana Izquierdo‐Domínguez, María José Castillo Marchuet, Cristina Cuevas Bravo, Leticia Domínguez Cereijo, Alicia Enríquez‐Matas, Ignacio Esteban Gorgojo, Adrián Germán Sánchez, Alba Juárez Guerrero   +11 more
wiley   +1 more source

Depósitos de patentes pelas IES de Santa Catarina: um estudo métrico da inovação [PDF]

, 2013
TCC (graduação) - Universidade Federal de Santa Catarina, Centro de Ciências da Educação, Curso de Biblioteconomia.O desenvolvimento em inovação pelas Instituições de Ensino Superior e de Pesquisa de Santa Catarina vive um crescimento.
Moraes, Clarissa Kellermann de, Moraes, Clarissa Kellerman de   +1 more
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Vobramitamab duocarmazine, an anti–B7‐H3 antibody–drug conjugate, in patients with advanced solid tumors: Final results of a phase 1 cohort expansion

Cancer, Volume 132, Issue 15, 1 August 2026.
Abstract Background Vobramitamab duocarmazine is an investigational antibody–drug conjugate (ADC) targeting B7 homolog 3 (B7‐H3) with a cytotoxic duocarmycin‐based DNA‐alkylating payload. This study evaluated its safety and antitumor activity in advanced solid tumors.
Eugene Shenderov, Manish R. Sharma, Elena Garralda, John Powderly, Iwona Ługowska, Alexander Spira, Marc Cucurull Salamero, Sekwon Jang, Rasha Cosman, John Shen, Wen Xu, Piotr J. Wysocki, Rodryg Ramlau, Emmanuel S. Antonarakis, Andrew J. Weickhardt, Jakub Żołnierek, Emiliano Calvo, Enxu Zhao, Chet Bohac, Ashley Ward, Girish Mallesara   +20 more
wiley   +1 more source

A inovação nas incubadoras tecnológicas :: uma análise sob a ótica das patentes / [PDF]

, 1999
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro Sócio-Econômico.Resultado de uma pesquisa realizada com 73 empresas residentes em 9 incubadoras tecnológicas no Brasil, a proposta deste estudo é analisar as inovações desenvolvidas ...
Prado, Evandro José da Silva
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