Results 51 to 60 of about 3,938,514 (291)

Path Similarity Analysis: a Method for Quantifying Macromolecular Pathways

, 2015
Diverse classes of proteins function through large-scale conformational changes; sophisticated enhanced sampling methods have been proposed to generate these macromolecular transition paths. As such paths are curves in a high-dimensional space, they have
Beckstein, Oliver, Kumar, Avishek, Seyler, Sean L., Thorpe, Michael F.   +3 more
core   +3 more sources

Position Measurement for a Relativistic Particle: Restricted-Path-Integral Analysis [PDF]

, 1995
Measurements of the position of a relativistic particle is considered in the framework of the Restricted-Path-Integral (RPI) approach. The amplitude describing such a measurement is shown to be exponentially small outside the light cone of the space-time
Aharonov, Aharonov, Aharonov, Barchielli, Caves, Caves, Diosi, Diosi, Feynman, Finkelstein, Finkelstein, Hellwig, Horst von Borzeszkowski, Khalili, Malin, Mensky, Mensky, Mensky, Michael B. Mensky, Mosley, Squires, Stueckelberg, Stueckelberg, von Borzeszkowski   +23 more
core   +3 more sources

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Novel Oral Polio Vaccine Type 2 Use for Polio Outbreak Response: A Global Effort for a Global Health Emergency

Pathogens
A sharp rise in circulating vaccine-derived poliovirus type 2 (cVDPV2) outbreaks in the years following the cessation of routine use of poliovirus type 2-containing oral polio vaccine and the trend of seeding new emergences with suboptimal vaccination ...
Feyrouz Damji Kurji, Ananda Sankar Bandyopadhyay, Simona Zipursky, Laura V. Cooper, Chris Gast, Margaret Toher, Ralf Clemens, Sue Ann Costa Clemens, Rayasam Prasad, Adriansjah Azhari   +9 more
doaj   +1 more source

Predicting posttraumatic stress disorder symptoms and pain intensity following severe injury: the role of catastrophizing [PDF]

European Journal of Psychotraumatology, 2011
Background: A number of theories have proposed possible mechanisms that may explain the high rates of comorbidity between posttraumatic stress disorder (PTSD) and persistent pain; however, there has been limited research investigating these factors ...
Jessica Carty, Meaghan O'Donnell, Lynette Evans, Nikolaos Kazantzis, Mark Creamer   +4 more
doaj   +1 more source

A shapley value approach to pricing climate risks [PDF]

, 2011
This paper prices the risk of climate change by calculating a lower bound for the price of a virtual insurance policy against climate risks associated with the business as usual (BAU) emissions path. In analogy with ordinary insurance pricing, this price
Cooke, Roger M
core   +2 more sources

YlmG1 is localized exclusively to the chloroplast envelope membrane and is involved in preprotein translocation in Arabidopsis thaliana

FEBS Open Bio, EarlyView.
Cytosolically synthesized chloroplast preproteins are translocated across the outer and inner envelope membranes through translocons called TOC and TIC, respectively. In green algae and plants, the TIC core is composed of essential membrane proteins, Tic12, Tic20, and Tic214.
Mengyi Li, Xueyang Zhao, Masato Nakai
wiley   +1 more source

Suppression of lung adenocarcinoma migration through organelle alkalization by human lactoferrin – albumin fusion

FEBS Open Bio, EarlyView.
This paper reveals how human lactoferrin–albumin fusion (hLF‐HSA) potently suppresses lung adenocarcinoma cell migration. hLF‐HSA upregulates NHE7, leading to Golgi alkalization, disruption of the Golgi secretome, downregulation of MMP1, and reversal of EMT. These findings suggest a novel Golgi‐targeting strategy to suppress cancer cell migration.
Hana Nopia, Masahiro Kimura, Daisuke Kurimoto, Atsushi Sato   +3 more
wiley   +1 more source

PATH ANALYSIS OF FACTORS INFLUENCING CASHLESS SOCIETY DEVELOPMENT USING BOOTSTRAP RESAMPLING

Barekeng
Path analysis can be applied to various fields, one of which is the field of banking economics. This study is aimed to examine what factors significantly affect the development of cashless society both directly and indirectly.
Dea Saraswati Pramaningrum, Adji Achmad Rinaldo Fernandes, Atiek Iriany, Solimun Solimun   +3 more
doaj   +1 more source

Genetic Variability Induced by Gamma Rays and Preliminary Results of Low-Cost TILLING on M2 Generation of Chickpea (Cicer arietinum L.)

Frontiers in Plant Science, 2018
In order to increase genetic variability for chickpea improvement, the Kabuli genotype, variety Ghab4, was treated with 280 Grays of gamma rays (Cobalt 60). Field characterization began with the M2 generation.
Wahiba Amri-Tiliouine, Wahiba Amri-Tiliouine, Meriem Laouar, Aissa Abdelguerfi, Joanna Jankowicz-Cieslak, Ljupcho Jankuloski, Bradley J. Till, Bradley J. Till   +7 more
doaj   +1 more source