Results 31 to 40 of about 515,998 (291)
ISPRS International Journal of Geo-Information, 2019 The topic of technology development and its disruptive effects has been the subject of much debate over the last 20 years with numerous theories at both macro and micro scales offering potential models of technology progression and disruption. This paper
Roger C. Brackin +3 more
doaj +1 more source
Mapping the evolution of mitochondrial complex I through structural variation
FEBS Letters, EarlyView.Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
Ankara Avrupa Çalışmaları Dergisi, 2023 After the Athens Agreement signed with Greece, Turkey became the second associate member of the EEC with ister kin duthe signature of the 1963 Ankara Agreement which established an institutionalized pathway that is open to interpretation and contestation
Zeynep Özde Ateşok
doaj +1 more source
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
P145 MEASUREMENT OF BLOOD PRESSURE DEPENDENCY OF CAROTID-FEMORAL PULSE WAVE VELOCITY
Artery Research, 2017 Background: Carotid-femoral pulse wave velocity (cfPWV) is predictive of cardiovascular outcomes but clinical interpretation is confounded by blood pressure (BP) interaction.
Mark Butlin +4 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
On distribution formulas for complex and $\ell$-adic polylogarithms
, 2020 We study an $\ell$-adic Galois analogue of the distribution formulas for polylogarithms with special emphasis on path dependency and arithmetic behaviors.
H Gangl +6 more
core +1 more source
On application of least-delay variation problem in ethernet networks using SDN concept [PDF]
, 2016 The goal of this paper is to present an application idea of SDN in Smart Grids, particularly, in the area of L2 multicast as defined by IEC 61850-9-2.
Boháč, Leoš +2 more
core +2 more sources
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source