Results 31 to 40 of about 44,961 (259)
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Path-Dependency and Emergent Computing under Vectorial Driving
Physical Review XThe sequential response of frustrated materials—ranging from crumpled sheets and amorphous media to metamaterials—reveals their memory effects and emergent computational potential.
C. M. Meulblok +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
IEEE AccessIn this paper, we propose a height-dependency shaping parameter ( $m$ ) and a height-dependency path-loss exponent for modelling small-scale Nakagami- $m$ fading and a large-scale path-loss model for unmanned aerial vehicle (UAV)-assisted network coded ...
Pankaj Kumar, Sudhan Majhi
doaj +1 more source
MARKET VERSUS GOVERNMENT IN THE LIGHT OF THE DISCUSSION ABOUT PATH DEPENDENCE
Ekonomia i Prawo, 2010 In the 1980s Brian Arthur and Paul David proposed methods which made possible to grasp the phenomenon of path dependency on the ground of economic theory.
Joanna Dzionek-Kozłowska
doaj +1 more source
Exploring psychosocial factors that influence smartphone dependency among Korean adolescents.
PLoS ONE, 2020 This study investigated the relationships among psychosocial factors that contribute to smartphone dependency among South Korean adolescents. This cross-sectional study involved the secondary data analysis of the 2016 Korean Children and Youth Panel ...
Hyeon Sik Chu, Young Ran Tak, Hanyi Lee
doaj +1 more source
Structure‐forward targeting of claudins with synthetic binders
FEBS Letters, EarlyView.Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley +1 more source
Path Dependency and Communal Tolerance in Indonesia
Studies of Transition States and Societies, 2017 Book review Menchik, Jeremy (2016). Islam and Democracy in Indonesia: Tolerance without Liberalism.
Gde Dwitya Arief Metera
doaj
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source