Results 231 to 240 of about 2,216,177 (285)

High‐Throughput Generation of Tumor Spheroids via Droplet Microfluidics for siRNA‐Loaded Nanomedicine Assessment

open access: yesAdvanced Healthcare Materials, EarlyView.
A droplet microfluidic platform is employed to enable high‐throughput, uniform tumor spheroid generation for evaluating siRNA‐loaded nanomedicines at the protein level. As a proof of concept, breast (MCF‐7) and brain (U87 MG) cancer cell lines are investigated using this platform, revealing penetration profiles and therapeutic responses between the two
Ling Liu   +4 more
wiley   +1 more source

Laser‐Assisted Processing and Modification of Bioactive Glasses: A Review

open access: yesAdvanced Healthcare Materials, EarlyView.
Laser technologies provide powerful tools to process and transform bioactive glasses for advanced biomedical applications. This review discusses laser‐matter interaction mechanisms, laser surface engineering, and laser‐assisted fabrication of scaffolds and nanofibers.
Antonio Riveiro   +8 more
wiley   +1 more source

Dual‐Peptide Nanoplatform: Mesoporous Silica Nanoparticles Functionalized With a Cell‐Penetrating Peptide and Loaded With Rationally Designed Antimicrobial Peptides for Tuberculosis Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Machine learning–guided engineering of a plectasin‐derived peptide yields DC05, a potent antimycobacterial candidate. Encapsulation into tuftsin‐functionalized mesoporous silica nanoparticles enhances intracellular delivery, stability, and activity against Mycobacterium tuberculosis while maintaining low cytotoxicity and minimal hemolysis. The combined
Christian S. Carnero Canales   +12 more
wiley   +1 more source

Advanced 3D Platforms for Modeling CNS Neuroinflammation: Cell Integration, Techniques, and Challenges

open access: yesAdvanced Healthcare Materials, EarlyView.
This review summarizes the roles of key central nervous system cell types, the extracellular matrix, and the blood‐brain barrier in neuroinflammation, and their integration into diverse 3D culture systems. It examines major incorporation strategies, including direct co‐culture, hydrogel encapsulation, transwell migration assays, and bioprinting ...
Emmanuelle D. Aiyegbusi   +2 more
wiley   +1 more source

Optoelectrical Devices for Neural Interfacing: Engineering Integration, Stability, and Multimodal Sensing

open access: yesAdvanced Healthcare Materials, EarlyView.
Implantable optoelectrical devices are an effective resource for the modulation and monitoring of neural activity with high spatiotemporal resolution. This review discusses current challenges faced by these devices and outlines future perspectives for the development of next‐generation neural interfaces targeting chronic, multisite, and multimodal ...
Stella Aslanoglou   +4 more
wiley   +1 more source

ETV2 Mediated Differentiation of Human Pluripotent Stem Cells Results in Functional Endothelial Cells for Engineering Advanced Vascularized Microphysiological Models

open access: yesAdvanced Healthcare Materials, EarlyView.
A robust method to generate functional human iPSC‐derived endothelial cells using inducible ETV2 expression. These cells self‐organize into stable, lumenized microvascular networks within microfluidic chips, surpassing conventional differentiation methods.
Shun Zhang   +12 more
wiley   +1 more source

Limited Log-Distance Path Loss Model Path Loss Exponent Estimation using Deep Deterministic Policy Gradient

SoutheastCon 2021, 2021
Low-cost wireless devices often rely on the log-distance path loss model for determining the distance between two devices based on radio signal strength. The log-distance path loss model relies on a properly determined path-loss exponent to produce accurate results; however, this variable can be difficult to obtain or estimate accurately, especially ...
David P. Grabowsky   +2 more
openaire   +1 more source

Comparison of Empirical Path Loss Propagation Models with Building Penetration Path Loss Model

International Journal on Communications Antenna and Propagation (IRECAP), 2016
Path loss Propagation models plays a fundamental role in planning and designing of mobile radio communication link. In this paper a building penetration path loss model was developed using AUTOCAD. The model involved the combination of three mechanisms of signal propagation; refraction, reflection and diffraction.
Promise Elechi, Paul Osaretin Otasowie
openaire   +1 more source

Multiplicative based path loss model

International Journal of Communication Systems, 2018
SummaryWe present a newly introduced multiplicative based path loss model for the wireless channel. The model verified with experimental data at 2100 MHz collected across Cyprus in 6 existing microcells in urban, suburban, and rural areas. The new method uses the multiplicative least square fitting model that relates the decibel path loss to the ...
Bülent Bilgehan, Stephen Ojo
openaire   +1 more source

Validation of path loss by heuristic prediction tool with path loss and RSSI measurements

2010 IEEE Antennas and Propagation Society International Symposium, 2010
The characterization of path loss in indoor environments has been the subject of extensive research and many models have been proposed to make accurate predictions. Statistical models are easy to obtain when a lot of measurement data are available, but their validity is limited to the category of buildings in which the measurements are performed.
D Plets   +7 more
openaire   +1 more source

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