Results 161 to 170 of about 4,917 (252)
Chronic low back pain in patients without advanced disc degeneration is associated with gut microbiome dysbiosis, marked by reduced microbial diversity and altered bacterial composition. These findings support a gut–disk axis in which impaired gut barrier integrity and systemic inflammation may contribute to disc inflammation, nociceptive fiber ...
Stone Sima +10 more
wiley +1 more source
Phenotypic characterization and complete genome of a tumorigenic pathobiont Escherichia coli LI60C3
Background Symbiotic microbes benefit the host, but the emergence of pathobionts leads to disease. An invasive Escherichia coli LI60C3, isolated from mouse colonocytes, shows colitogenic and tumorigenic properties.
Shu-Chen Wei +7 more
core +1 more source
Gut Microbiota as a Key Modulator in the Pathophysiology of Sepsis: SURVEIL Project
Longitudinal profiling of 132 hospitalized patients reveals that age, colonization status, and sepsis interact to shape gut microbiota diversity and composition. Sepsis is associated with reduced alpha diversity, beta‐diversity shifts, functional predictions (methanogenesis, nitrate/sulfate respiration), and partial MDR overlap with bloodstream ...
Chiara Bazzano +22 more
wiley +1 more source
Goblet of fire: how Chlamydia ignites region-specific colitis by hijacking goblet cells. [PDF]
McCole DF.
europepmc +1 more source
Exploring the Antimicrobial Potential of Vanadium‐Based MXenes for Biomedical Applications
Vanadium‐based MXenes (V₂CTₓ and V₄C₃Tₓ) exhibit moderate antibacterial activity against E. coli and S. aureus, mainly through mechanical “nano‐knife” membrane disruption rather than ROS generation. These nanomaterials show good biocompatibility and highlight the importance of standardized experimental models for evaluating MXene antimicrobial ...
Roberto Rosato +13 more
wiley +1 more source
Impaired systemic antibody response against gut microbiota pathobionts in critical illness and susceptibility to nosocomial infections. [PDF]
Cho NA +6 more
europepmc +1 more source
BACKGROUND & AIMS Primary sclerosing cholangitis (PSC), often associated with inflammatory bowel disease (IBD), presents a multifactorial etiology involving genetic, immunologic, and environmental factors.
Seidel, Gerald +30 more
core +1 more source
Fungal‐Bacterial Interactions in Polymicrobial Infections: Hidden Threats
ABSTRACT Polymicrobial infections involving fungi and bacteria represent a major and increasingly recognized clinical challenge, in which interkingdom interactions significantly amplify disease severity, antimicrobial resistance, and treatment failure. Rather than passive co‐existence, fungal–bacterial communities form highly coordinated systems driven
Mohammad Javad Roustaye Gourabi +3 more
wiley +1 more source
Acetate‐Linked Energy Metabolism as a Determinant of Early Haemophilus influenzae Infection Fitness
The Pta–AckA pathway is critical for Haemophilus influenzae energy generation, metabolic homeostasis, stress resistance, and intracellular colonization, highlighting its potential as a target for management of H. influenzae infections.
Marufa Nasreen +8 more
wiley +1 more source
Gut microbiome plays a crucial role in colorectal cancer development. The advanced sequencing techniques have the potential to complement current non‐invasive methods for early diagnosis and prevention of colorectal cancer. This includes conducting studies with robust statistical power and consistent, replicable methodologies, taking into consideration
Parvin Askari +10 more
wiley +1 more source

