Results 161 to 170 of about 4,917 (252)

Patients With Chronic Low Back Pain Without Advanced Disk Degeneration Exhibit Gut Microbiome Dysbiosis: Evidence From an Age‐, Sex‐, and BMI‐Matched Pilot Study

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Chronic low back pain in patients without advanced disc degeneration is associated with gut microbiome dysbiosis, marked by reduced microbial diversity and altered bacterial composition. These findings support a gut–disk axis in which impaired gut barrier integrity and systemic inflammation may contribute to disc inflammation, nociceptive fiber ...
Stone Sima   +10 more
wiley   +1 more source

Phenotypic characterization and complete genome of a tumorigenic pathobiont Escherichia coli LI60C3

open access: yes
Background Symbiotic microbes benefit the host, but the emergence of pathobionts leads to disease. An invasive Escherichia coli LI60C3, isolated from mouse colonocytes, shows colitogenic and tumorigenic properties.
Shu-Chen Wei   +7 more
core   +1 more source

Gut Microbiota as a Key Modulator in the Pathophysiology of Sepsis: SURVEIL Project

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Longitudinal profiling of 132 hospitalized patients reveals that age, colonization status, and sepsis interact to shape gut microbiota diversity and composition. Sepsis is associated with reduced alpha diversity, beta‐diversity shifts, functional predictions (methanogenesis, nitrate/sulfate respiration), and partial MDR overlap with bloodstream ...
Chiara Bazzano   +22 more
wiley   +1 more source

Exploring the Antimicrobial Potential of Vanadium‐Based MXenes for Biomedical Applications

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Vanadium‐based MXenes (V₂CTₓ and V₄C₃Tₓ) exhibit moderate antibacterial activity against E. coli and S. aureus, mainly through mechanical “nano‐knife” membrane disruption rather than ROS generation. These nanomaterials show good biocompatibility and highlight the importance of standardized experimental models for evaluating MXene antimicrobial ...
Roberto Rosato   +13 more
wiley   +1 more source

Gut Pathobiont-Derived Outer Membrane Vesicles Drive Liver Inflammation and Fibrosis in Primary Sclerosing Cholangitis-Associated Inflammatory Bowel Disease

open access: yes
BACKGROUND & AIMS Primary sclerosing cholangitis (PSC), often associated with inflammatory bowel disease (IBD), presents a multifactorial etiology involving genetic, immunologic, and environmental factors.
Seidel, Gerald   +30 more
core   +1 more source

Fungal‐Bacterial Interactions in Polymicrobial Infections: Hidden Threats

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
ABSTRACT Polymicrobial infections involving fungi and bacteria represent a major and increasingly recognized clinical challenge, in which interkingdom interactions significantly amplify disease severity, antimicrobial resistance, and treatment failure. Rather than passive co‐existence, fungal–bacterial communities form highly coordinated systems driven
Mohammad Javad Roustaye Gourabi   +3 more
wiley   +1 more source

Acetate‐Linked Energy Metabolism as a Determinant of Early Haemophilus influenzae Infection Fitness

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
The Pta–AckA pathway is critical for Haemophilus influenzae energy generation, metabolic homeostasis, stress resistance, and intracellular colonization, highlighting its potential as a target for management of H. influenzae infections.
Marufa Nasreen   +8 more
wiley   +1 more source

Fecal Microbiome Alterations in Colorectal Cancer: A Systematic Review of Compositional Changes and Microbial Biomarkers

open access: yesMicrobiologyOpen, Volume 15, Issue 3, June 2026.
Gut microbiome plays a crucial role in colorectal cancer development. The advanced sequencing techniques have the potential to complement current non‐invasive methods for early diagnosis and prevention of colorectal cancer. This includes conducting studies with robust statistical power and consistent, replicable methodologies, taking into consideration
Parvin Askari   +10 more
wiley   +1 more source

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