Results 151 to 160 of about 5,803 (234)

Sepsis: Epidemiology, Pathophysiology, and Management

MedComm, Volume 7, Issue 11, November 2026.
Sepsis remains a major global health burden characterized by substantial geographical heterogeneity and a considerable disease burden in China. Its pathophysiology reflects an interconnected network involving excessive inflammation, oxidative stress, immune imbalance and immunoparalysis, mitochondrial damage, endothelial injury, gut dysbiosis ...
Guang‐Tao Pan, Yu Deng, Lin‐Rui Ma, Yu‐Tong Li, Yu Qian, Yi‐Hua Ma, Hai‐Wei Rao, Yi‐Zhun Zhu, Pei‐Yu Yan   +8 more
wiley   +1 more source

Shotgun Metagenomic Analysis Reveals Taxonomic and Functional Transitions in the Salivary Microbiome During Periodontal Disease Progression

Journal of Clinical Periodontology, Volume 53, Issue 11, Page 1650-1662, November 2026.
ABSTRACT Aim To characterise multi‐kingdom salivary microbiome profiles across clinically defined periodontal states and identify stage‐specific taxonomic and functional alterations using shotgun metagenomic sequencing. Materials and Methods In this cross‐sectional study, 204 adults (mean age 40.3 ± 7.6 years) from the SECRETO study (NCT01934725 ...
Muhammed Manzoor, Jaakko Leskelä, Eija Könönen, Leo Lahti, Jukka Putaala, Pirkko J. Pussinen, Susanna Paju   +6 more
wiley   +1 more source

Neisseria Species as Novel Respiratory Pathobionts in Bronchiectasis [PDF]

TP94. TP094 DISCOVERIES IN BACTERIAL AND VIRAL PNEUMONIA PATHOGENESIS, 2021
T. Jaggi, M. Mac Aogáin, H.R. Keir, A. Dicker, T. Xu, M.S. Koh, T.H. Ong, A.L.Y. Hou, J. Abisheganaden, T.B. Low, N.S. Tan, M. Fang, L. Liang, J.D. Chalmers, S.H. Chotirmall   +14 more
openaire   +1 more source

From Dysbiosis to Disease: How Vaginal Microbiota Shape Group B Streptococcus Pathogenesis

ChemBioChem, Volume 27, Issue 20, 28 October 2026.
Lactobacillus crispatus plays a critical role in the vaginal microbiome. Limiting glucose shifts metabolism toward HMO consumption and amino acid metabolism. These actions enable alkali production and competition. Homeostasis, characterized by dense Lactobacilli colonization and suppression of pathogens, provides resistance to dysbiosis.
Julie A. Talbert, Steven D. Townsend
wiley   +1 more source

Immune impact of commensals versus pathobionts [PDF]

American Journal of Transplantation, 2020
openaire   +1 more source

Shifting microbiomes: pathobionts hiding in our guts

eBioMedicine, 2023
openaire   +3 more sources

Pathobiont and symbiont contribute to microbiota homeostasis through Malpighian tubules–gut countercurrent flow in Bactrocera dorsalis

Host–gut microbiota interactions are more complex than good or bad. Both gut symbiotic bacteria and pathobionts can provide essential functions to their host in one scenario and yet be detrimental to host health in another.
Lemaitre, Bruno, Li, Xiaoxue, Bai, Shuai, Liu, Yanning, Luo, Rengang, Zhang, Hongyu   +5 more
core   +1 more source

Longitudinal ecological disruption and metabolite associations of the gut microbiome during acute myeloid leukemia therapy. [PDF]

Microbiol Spectr
Zhou J, Li R, Zhang M, Wu Y, Hu R.
europepmc   +1 more source

Functionally declining microbiota in chronic disease: beyond taxonomic loss. [PDF]

Gut Microbes
Kim HS.
europepmc   +1 more source

Colorectal laterally spreading tumors exhibit a distinct carcinogenic eco-metabolic shift defined by multi-omics profiling. [PDF]

Front Microbiol
Liu W, Liu J, Chen Y, Lu G, Shen J, Zheng X, Wei X.   +6 more
europepmc   +1 more source