Results 141 to 150 of about 4,917 (252)

A Gnotobiotic Mouse Model for Studying the Effect of Human Gut Community Ecology on a Pathobiont, Bacteroides fragilis

, 2015
OF THE DISSERTATION A Gnotobiotic Mouse Model for Studying the Effect of Human Gut Community Ecology on a Pathobiont, Bacteroides fragilis by Vitas Wagner Doctor of Philosophy in Biology and Biomedical Sciences Evolution, Ecology, and Population Biology ...
Wagner, Vitas
core   +1 more source

Characteristics of the Health‐Associated Oral Microbiome in Young Nonhuman Primates

Molecular Oral Microbiology, EarlyView.
The oral microbiome of healthy younger nonhuman primates, as a preclinical model of the human oral cavity, was evaluated. The results provide seminal details of the oral microbiome in this disease model to elucidate specific microbial changes.
J. L. Ebersole, O. A. Gonzalez
wiley   +1 more source

An expanded database and analytical toolkit for identifying bacterial virulence factors and their associations with chronic diseases

Nature Communications
Virulence factor genes (VFGs) play pivotal roles in bacterial infections and have been identified within the human gut microbiota. However, their involvement in chronic diseases remains poorly understood. Here, we establish an expanded VFG database (VFDB
Wanting Dong, Xinyue Fan, Yaqiong Guo, Siyi Wang, Shulei Jia, Na Lv, Tao Yuan, Yuanlong Pan, Yong Xue, Xi Chen, Qian Xiong, Ruifu Yang, Weigang Zhao, Baoli Zhu   +13 more
doaj   +1 more source

Aging: a possible road toward gut microbiota pathoadaptation

Gut Microbes
Laboratory-raised mice live approximately seven times longer and healthier lives compared to their wild counterparts, due to a standardized healthy diet and limited exposure to environmental stressors.
Rita Melo-Miranda, Ana Pinto, Hugo C. Barreto, Catarina S. H. Jesus, Isabel Gordo, Iola F. Duarte, Ana Sousa   +6 more
doaj   +1 more source

The yersiniabactin pathogenicity island of pathobiont E. coli promotes fibrosis in Il10-/- mice

, 2018
Intestinal fibrosis, defined as the excess deposition of extracellular matrix (ECM) as a result of chronic inflammation and dysregulated wound healing, afflicts more than 30% of patients with inflammatory bowel diseases (IBD), yet there is minimal ...
Moore, Lyndsey
core   +1 more source

Novel and emerging antimicrobial strategies in the management of oral infections

Periodontology 2000, EarlyView.
Abstract Background Antibiotics marked a pivotal turning point in human civilization, enhancing social interactions and extending human life expectancy. In addition to their success in treating systemic infectious diseases, they have significantly improved periodontal treatment outcomes as an adjunct therapy.
Ozge Unlu, Nil Yakar, Alpdogan Kantarci
wiley   +1 more source

Probiotic Engraftment and Suppression of Canine Otitis Externa Pathogens by Probiotic Ear Drops

Veterinary Dermatology, EarlyView.
Background: Lactobacillaceae have shown promise with their potential to outcompete pathogens and restore a healthy microbial balance in otitis externa (OE). Hypothesis/Objectives: This study aimed to evaluate the presence of viable Lactobacillaceae over time and in vitro ability to inhibit the growth of common OE pathogens.
Marta Salichs, Shea Beasley, Hanne Gagroo, Alix Simons, Tim Henkens, Josep Homedes, Ingmar Claes   +6 more
wiley   +1 more source

Clinical Management of Helicobacter Infection in Captive Baboons (Papio anubis and Papio hamadryas), and Isolation and Molecular Characterization of Three Novel Helicobacter Species

Journal of Medical Primatology, Volume 55, Issue 4, August 2026.
ABSTRACT Background Helicobacter spp. are gastric or enterohepatic bacteria that can be commensal, opportunistic, or pathogenic. Few studies have evaluated Helicobacter spp. in baboons. Methods Twenty‐seven captive baboons were surveyed for Helicobacter spp. by fecal PCR, and a subset evaluated by culture.
Isabel A. Jimenez, Courtney Lunger, Marcus J. Crim, Shannon L. Primm, Anthony Mannion, Nathan P. Crilly, Lydia M. Hopper, Lindsey G. Thurman, Linnette L. Vasquez, Cory Brayton, Yan Feng, James G. Fox, Zeli Shen, Jessica M. Izzi   +13 more
wiley   +1 more source

An inflammatory paradox: strategies inflammophilic oral pathobionts employ to exploit innate immunity via neutrophil manipulation

Frontiers in Oral Health
Inflammatory dysbiotic diseases present an intriguing biological paradox. Like most other infectious disease processes, the alarm bells of the host are potently activated by tissue-destructive pathobionts, triggering a cascade of physiological responses ...
Dustin L. Higashi, Hua Qin, Christina Borland, Jens Kreth, Jens Kreth, Justin Merritt, Justin Merritt   +6 more
doaj   +1 more source

Strain‐Specific Biotransformation of Grape Marc by Lactic Acid Bacteria: Genomic Validation and Gut Microbiota Modulation

Food Frontiers, Volume 7, Issue 4, July 2026.
ABSTRACT Grape marc (GM) is a polyphenol‐rich winery byproduct that remains underutilized due to its complex fiber matrix, which limits the bioaccessibility of bound phenolics. While lactic acid fermentation (LAF) can enhance the release of these compounds, the strain‐specific metabolic fate of GM phenolics during digestion and colonic fermentation ...
Ziyao Liu, Hanjing Wu, Brendan Holland, Colin J. Barrow, Hafiz A. R. Suleria   +4 more
wiley   +1 more source