Results 61 to 70 of about 5,803 (234)

Pathobiont-driven antibody sialylation through IL-10 undermines vaccination [PDF]

The pathobiont Staphylococcus aureus (Sa) induces nonprotective antibody imprints that underlie ineffective staphylococcal vaccination. However, the mechanism by which Sa modifies antibody activity is not clear.
Biswa Choudhruy, Lin, Brian, Irshad A. Hajam, Nathan E. Lewis, Choudhruy, Biswa, Austin W.T. Chiang, Brian Lin, Askarian, Fatemeh, Xin Du, Haining Li, Victor Nizet, Suzuki, Emi, Angelica M. Riestra, Gonzalez, Cesia, Li, Haining, Fatemeh Askarian, Douglas J. Conrad, Igor H. Wierzbicki, Tsai, Chih-Ming, George Y. Liu, Emi Suzuki, Ty’Tianna Clark, Chih-Ming Tsai, J.R. Caldera, Cesia Gonzalez, Du, Xin, David J. Gonzalez, Nizet, Victor, Riestra, Angelica M, Hajam, Irshad A, Caldera, JR, Conrad, Douglas J, Wierzbicki, Igor H, Lewis, Nathan E, Clark, Ty’Tianna, Gonzalez, David J, Liu, George Y, Chiang, Austin WT   +37 more
core   +1 more source

Data_Sheet_1_Insights From the Lactobacillus johnsonii Genome Suggest the Production of Metabolites With Antibiofilm Activity Against the Pathobiont Candida albicans.docx

, 2022
Lactobacillus johnsonii is a probiotic bacterial species with broad antimicrobial properties; however, its antimicrobial activities against the pathobiont Candida albicans are underexplored.
Angela Thompson (237630), Roberto Vazquez-Munoz (9120922), Anna Dongari-Bagtzoglou (237632), Yanjiao Zhou (158268), Takanori Sobue (6619811), Jordan T. Russell (12203570)   +5 more
core   +1 more source

Full-length 16S rRNA nanopore sequencing enables species resolution of Fusobacterium associated with colorectal cancer

Gut Microbes
Recent studies have revealed that the long-recognized link between the historically defined Fusobacterium nucleatum group and colorectal cancer is largely driven by Fusobacterium animalis.
William Rosenbaum, Marina Rubio Garcia, Anna Löfgren-Burström, Pär Larsson, Sofia Edin, Vicky Bronnec, Richard Palmqvist   +6 more
doaj   +1 more source

The Inhibitory Effect of Ileal Mucosal Media Originated from FVB/N Mice Strain on Escherichia coli LF82 Invasion

Bezmiâlem Science, 2019
Objective:The aim of this study was to investigate the effect of healthy mucosa on adhesive and invasive properties of AIEC reference strain Escherichia coli (E. coli) LF82.
Hüsamettin AYGÜN, Murat KARAMEŞE, Fikret UYAR   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Microbiological and Behavioural Determinants of Genital HPV Infections among Adolescent Girls and Young Women in South Africa

, 2021
Patterns of bacterial pathobiont infections according to vaginal HPV status among 192 AGYW. HPV-positive AGYW with (a) single infections, (b) dual infections, (c) triple infections; and HPV-negative AGYW with (d) single infections, (e) dual infections ...
Harris Onywera, Zizipho Z. A. Mbulawa, Sikhumbuzo A. Mabunda, Anna-Lise Williamson   +3 more
core   +2 more sources

Supramolecular Zinc–Polyphenol Coordination Assemblies Mitigate Colonic Inflammation by Regulating Mucosal Barrier and Microbiome

Advanced Science, EarlyView.
A carrier‐free zinc‐coordinated polyphenol nanoplatform (ZnCA NPs) is designed as an “all‐in‐one” therapeutic strategy for intestinal inflammation. The ZnCA NPs exhibit enhanced colonic accumulation and broad‐spectrum reactive oxygen and nitrogen species scavenging.
Qiwen Xie, Mai Ye, Xuexia Liu, Jing Wang, Ying Chen, Lu Tan, Jinheng Fu, Xiaochang Huang   +7 more
wiley   +1 more source

Periodontal microbiology and microbial etiology of periodontal diseases: Historical concepts and contemporary perspectives

Periodontology 2000, EarlyView., 2023
Abstract This narrative review summarizes the collective knowledge on periodontal microbiology, through a historical timeline that highlights the European contribution in the global field. The etiological concepts on periodontal disease culminate to the ecological plaque hypothesis and its dysbiosis‐centered interpretation.
Georgios N. Belibasakis, Daniel Belstrøm, Sigrun Eick, Ulvi K. Gursoy, Anders Johansson, Eija Könönen   +5 more
wiley   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Acute Infectious Gastroenteritis Potentiates a Crohn's Disease Pathobiont to Fuel Ongoing Inflammation in the Post-Infectious Period.

, 2016
Crohn's disease (CD) is a chronic inflammatory condition of diverse etiology. Exposure to foodborne pathogens causing acute gastroenteritis produces a long-term risk of CD well into the post-infectious period but the mechanistic basis for this ongoing ...
Joseph B McPhee, Brian K Coombes, Cherrie L Small, Lydia Xing, Hong T Law, Coombes Brian K., McPhee Joseph B., Law Hong T., Small Cherrie L., Xing Lydia   +9 more
core   +1 more source