Results 21 to 30 of about 18,034 (241)
A Broad-Spectrum Infection Diagnostic that Detects Pathogen-Associated Molecular Patterns (PAMPs) in Whole Blood [PDF]
EBioMedicine, 2016 Blood cultures, and molecular diagnostic tests that directly detect pathogen DNA in blood, fail to detect bloodstream infections in most infected patients. Thus, there is a need for a rapid test that can diagnose the presence of infection to triage patients, guide therapy, and decrease the incidence of sepsis.An Enzyme-Linked Lectin-Sorbent Assay ...
Cartwright, Mark +17 more
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Molecular Plant-Microbe Interactions, 2019 The importance of pattern-triggered immunity (PTI) in plant defense has been clearly established through genetic studies of mutants lacking functional pattern recognition receptors (PRRs) and signaling components downstream of PRR activation.
Qing Yan +2 more
doaj +1 more source
Post-Translational Modification of HMGB1 Disulfide Bonds in Stimulating and Inhibiting Inflammation
Cells, 2021 High mobility group box 1 protein (HMGB1), a highly conserved nuclear DNA-binding protein, is a “damage-associated molecular pattern” molecule (DAMP) implicated in both stimulating and inhibiting innate immunity.
Ulf Andersson +2 more
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iScience, 2021 Summary: Hepatitis B virus (HBV) mediates persistent infection, chronic hepatitis, and liver disease. HBV covalently closed circular (ccc)DNA is central to viral persistence such that its elimination is considered the cornerstone for HBV cure ...
Sooyoung Lee +5 more
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Rice, 2021 Background Avr-Pita was the first effector identified in the blast fungus (Magnaporthe oryzae)–rice (Oryza sativa) pathosystem. However, the molecular mechanism underlying its effects on the host plant has remained a long-standing mystery.
Jingluan Han +7 more
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Dissecting the molecular interactions between wheat and the fungal pathogen Zymoseptoria tritici
Frontiers in Plant Science, 2016 The Dothideomycete fungus Zymoseptoria tritici (previously known as Mycosphaerella graminicola and Septoria tritici) is the causative agent of Septoria tritici leaf blotch (STB) disease of wheat (Triticum aestivum L.).
Graeme James Kettles, Kostya eKanyuka
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Crop Journal, 2023 Plants use a sophisticated immune system to perceive pathogen infection and activate immune responses in a tightly controlled manner. In barley, HvWRKY2 acts as a repressor in barley disease resistance to the powdery mildew fungus, Blumeria graminis f ...
Deshui Yu +12 more
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Effects of low dose GM-CSF on microglial inflammatory profiles to diverse pathogen-associated molecular patterns (PAMPs) [PDF]
Journal of Neuroinflammation, 2007 It is well appreciated that obtaining sufficient numbers of primary microglia for in vitro experiments has always been a challenge for scientists studying the biological properties of these cells. Supplementing culture medium with granulocyte-macrophage colony-stimulating factor (GM-CSF) partially alleviates this problem by increasing microglial yield.
Esen, Nilufer, Kielian, Tammy
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Safety of Therapeutic Fever Induction in Cancer Patients Using Approved PAMP Drugs
Translational Oncology, 2018 William Coley, between 1895 and 1936, treated hundreds of cancer patients using infusions of fever inducing bacerial extracts. Similar experiments were done by Klyuyeva and co-workers in the 1940ies in Russia using trypanosoma extracts.
Uwe Rudolf Max Reuter +2 more
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Frontiers in Plant Science, 2020 Pathogen-associated molecular pattern (PAMP) recognition occurs by plasma membrane located receptors that induce among other processes nuclear gene expression.
Mai Jarad +6 more
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